The Resource Aging Research in Yeast, edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun, (electronic resource)

Aging Research in Yeast, edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun, (electronic resource)

Label
Aging Research in Yeast
Title
Aging Research in Yeast
Statement of responsibility
edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun
Creator
Contributor
Editor
Provider
Subject
Language
eng
Summary
This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined
Member of
http://library.link/vocab/creatorName
Breitenbach, Michael
Image bit depth
0
LC call number
QH301-705
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Jazwinski, S. Michal.
  • Laun, Peter.
  • SpringerLink
Series statement
Subcellular Biochemistry,
Series volume
57
http://library.link/vocab/subjectName
  • Life sciences
  • Geriatrics
  • Cytology
  • Microbiology
  • Life Sciences
  • Life Sciences, general
  • Geriatrics/Gerontology
  • Cell Biology
  • Apoptosis
  • Oxidative Stress
  • Microbiology
Label
Aging Research in Yeast, edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. Preface and Introduction to Aging research in Yeast -- 2.Oxidative stresses and ageing -- 3.The role of Mitochondria in the aging processes of yeast -- 4.The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Aging -- 5. Chronological Aging in Saccharomyces cerevisiae -- 6. Still waters run deep: Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- 7. Maximising the yeast chronological lifespan -- 8.Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae -- 9. DNA damage and DNA replication stress in yeast models of aging -- 10.Yeast aging and apoptosis.-11. Cellular homeostasis in fungi: Impact on the aging process -- 12.Genome-wide analysis of yeast aging -- 13. Genetic Approaches to Aging in Budding and Fission Yeasts: New Connections and New Opportunities -- 14. Evolution of asymmetric damage segregation: a modelling approach.-15. Cellular ageing and the actin cytoskeleton
Dimensions
unknown
Extent
XII, 368 p.
File format
multiple file formats
Form of item
electronic
Isbn
9789400725614
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-007-2561-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-94-007-2561-4
Label
Aging Research in Yeast, edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. Preface and Introduction to Aging research in Yeast -- 2.Oxidative stresses and ageing -- 3.The role of Mitochondria in the aging processes of yeast -- 4.The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Aging -- 5. Chronological Aging in Saccharomyces cerevisiae -- 6. Still waters run deep: Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- 7. Maximising the yeast chronological lifespan -- 8.Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae -- 9. DNA damage and DNA replication stress in yeast models of aging -- 10.Yeast aging and apoptosis.-11. Cellular homeostasis in fungi: Impact on the aging process -- 12.Genome-wide analysis of yeast aging -- 13. Genetic Approaches to Aging in Budding and Fission Yeasts: New Connections and New Opportunities -- 14. Evolution of asymmetric damage segregation: a modelling approach.-15. Cellular ageing and the actin cytoskeleton
Dimensions
unknown
Extent
XII, 368 p.
File format
multiple file formats
Form of item
electronic
Isbn
9789400725614
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-007-2561-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-94-007-2561-4

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