Coverart for item
The Resource Biomedical Applications of Acridines : Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases, by Jan Ježek, Jan Hlaváček, Jaroslav Šebestík, (electronic resource)

Biomedical Applications of Acridines : Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases, by Jan Ježek, Jan Hlaváček, Jaroslav Šebestík, (electronic resource)

Label
Biomedical Applications of Acridines : Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases
Title
Biomedical Applications of Acridines
Title remainder
Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases
Statement of responsibility
by Jan Ježek, Jan Hlaváček, Jaroslav Šebestík
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy
Member of
http://library.link/vocab/creatorName
Ježek, Jan
Image bit depth
0
LC call number
RS400-431
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Hlaváček, Jan.
  • Šebestík, Jaroslav.
  • SpringerLink
Series statement
Progress in Drug Research,
Series volume
72
http://library.link/vocab/subjectName
  • Chemistry
  • Neurochemistry
  • Pharmacology
  • Bioorganic chemistry
  • Pharmaceutical chemistry
  • Nucleic acids
  • Proteins
  • Chemistry
  • Medicinal Chemistry
  • Neurochemistry
  • Pharmacology/Toxicology
  • Protein-Ligand Interactions
  • Bioorganic Chemistry
  • Nucleic Acid Chemistry
Label
Biomedical Applications of Acridines : Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases, by Jan Ježek, Jan Hlaváček, Jaroslav Šebestík, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preliminary ToC 1 Introduction -- 2 Nomenclature -- 3. Syntheses -- 4. Interactions of acridines with nucleic acids -- 5. Intercations with proteins -- 6. Applications for treament of neurodegenerative diseases -- 7. Some applications of selective toxicities of acridines -- 8. Acridine on dendrimeric carriers -- 9 Acridines used for staining -- 10 Miscellaneous -- 11 Conclusions and outlook
Dimensions
unknown
Extent
XIII, 237 p. 79 illus., 25 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319639536
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-63953-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-63953-6
Label
Biomedical Applications of Acridines : Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases, by Jan Ježek, Jan Hlaváček, Jaroslav Šebestík, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preliminary ToC 1 Introduction -- 2 Nomenclature -- 3. Syntheses -- 4. Interactions of acridines with nucleic acids -- 5. Intercations with proteins -- 6. Applications for treament of neurodegenerative diseases -- 7. Some applications of selective toxicities of acridines -- 8. Acridine on dendrimeric carriers -- 9 Acridines used for staining -- 10 Miscellaneous -- 11 Conclusions and outlook
Dimensions
unknown
Extent
XIII, 237 p. 79 illus., 25 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319639536
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-63953-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-63953-6

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