The Resource Bone Morphogenetic Proteins: Systems Biology Regulators, edited by Slobodan Vukicevic, Kuber T. Sampath, (electronic resource)

Bone Morphogenetic Proteins: Systems Biology Regulators, edited by Slobodan Vukicevic, Kuber T. Sampath, (electronic resource)

Label
Bone Morphogenetic Proteins: Systems Biology Regulators
Title
Bone Morphogenetic Proteins: Systems Biology Regulators
Statement of responsibility
edited by Slobodan Vukicevic, Kuber T. Sampath
Contributor
Editor
Provider
Subject
Language
eng
Summary
This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia
Member of
Image bit depth
0
LC call number
QR180-189.5
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Vukicevic, Slobodan.
  • Sampath, Kuber T.
  • SpringerLink
Series statement
Progress in Inflammation Research
http://library.link/vocab/subjectName
  • Medicine
  • Immunology
  • Proteins
  • Cytokines
  • Growth factors
  • Systems biology
  • Cytology
  • Biomedicine
  • Immunology
  • Cell Biology
  • Cytokines and Growth Factors
  • Protein Science
  • Systems Biology
Label
Bone Morphogenetic Proteins: Systems Biology Regulators, edited by Slobodan Vukicevic, Kuber T. Sampath, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- BMPs: Historic and Future Perspectives -- BMP – Biology -- BMPs in Development -- BMP signaling -- BMP Antagonists - Biology -- BMP and BMP Antagonists - Structure and Function -- BMPs in Orthopaedic Medicine: Promises and Challenges -- BMP6 and Bone Repair -- BMPs in Dental Medicine: Promises and Challenges -- BMPs in Spine -- BMPs in Articular Joints -- BMP Signaling & FOP -- BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases -- BMPs in Inflammation -- BMPs and Angiogenesis -- BMP Signaling in Iron Homeostasis -- BMP Signaling in Pulmonary Arterial Hypertension -- BMP Signaling and Cancer -- BMP Biology in Rare Diseases
Dimensions
unknown
Extent
XII, 445 p. 43 illus., 32 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319475073
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-47507-3
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-47507-3
Label
Bone Morphogenetic Proteins: Systems Biology Regulators, edited by Slobodan Vukicevic, Kuber T. Sampath, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- BMPs: Historic and Future Perspectives -- BMP – Biology -- BMPs in Development -- BMP signaling -- BMP Antagonists - Biology -- BMP and BMP Antagonists - Structure and Function -- BMPs in Orthopaedic Medicine: Promises and Challenges -- BMP6 and Bone Repair -- BMPs in Dental Medicine: Promises and Challenges -- BMPs in Spine -- BMPs in Articular Joints -- BMP Signaling & FOP -- BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases -- BMPs in Inflammation -- BMPs and Angiogenesis -- BMP Signaling in Iron Homeostasis -- BMP Signaling in Pulmonary Arterial Hypertension -- BMP Signaling and Cancer -- BMP Biology in Rare Diseases
Dimensions
unknown
Extent
XII, 445 p. 43 illus., 32 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319475073
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-47507-3
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-47507-3

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