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The Resource CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis, Yu Jiang, Nanyang Technological University, Singapore, Mei Yan, Illumina, US, Xiwei Huang, Hangzhou Dianzi University, China, Hao Yu, Nanyang Technological University, Singapore

CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis, Yu Jiang, Nanyang Technological University, Singapore, Mei Yan, Illumina, US, Xiwei Huang, Hangzhou Dianzi University, China, Hao Yu, Nanyang Technological University, Singapore

Label
CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis
Title
CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis
Statement of responsibility
Yu Jiang, Nanyang Technological University, Singapore, Mei Yan, Illumina, US, Xiwei Huang, Hangzhou Dianzi University, China, Hao Yu, Nanyang Technological University, Singapore
Creator
Contributor
Author
Provider
Publisher
Subject
Language
eng
Summary
  • A thorough examination of lab-on-a-chip circuit-level operations to improve system performance A rapidly aging population demands rapid, cost-effective, flexible, personalized diagnostics. Existing systems tend to fall short in one or more capacities, making the development of alternatives a priority. CMOS Integrated Lab-on-a-Chip System for Personalized Biomedical Diagnosis provides insight toward the solution, with a comprehensive, multidisciplinary reference to the next wave of personalized medicine technology. A standard complementary metal oxide semiconductor (CMOS) fabrication technology allows mass-production of large-array, miniaturized CMOS-integrated sensors from multi-modal domains with smart on-chip processing capability. This book provides an in-depth examination of the design and mechanics considerations that make this technology a promising platform for microfluidics, micro-electro-mechanical systems, electronics, and electromagnetics. From CMOS fundamentals to end-us
  • er applications, all aspects of CMOS sensors are covered, with frequent diagrams and illustrations that clarify complex structures and processes. Detailed yet concise, and designed to help students and engineers develop smaller, cheaper, smarter lab-on-a-chip systems, this invaluable reference: -Provides clarity and insight on the design of lab-on-a-chip personalized biomedical sensors and systems -Features concise analyses of the integration of microfluidics and micro-electro-mechanical systems -Highlights the use of compressive sensing, super-resolution, and machine learning through the use of smart SoC processing -Discusses recent advances in complementary metal oxide semiconductor-integrated lab-on-a-chip systems -Includes guidance on DNA sequencing and cell counting applications using dual-mode chemical/optical and energy harvesting sensors The conventional reliance on the microscope, flow cytometry, and DNA sequencing leaves diagnosticians tied to bulky, expensive equipment with
  • a central problem of scale. Lab-on-a-chip technology eliminates these constraints while improving accuracy and flexibility, ushering in a new era of medicine. This book is an essential reference for students, researchers, and engineers working in diagnostic circuitry and microsystems.'
Cataloging source
DLC
http://library.link/vocab/creatorDate
1990-
http://library.link/vocab/creatorName
Jiang, Yu
Index
index present
LC call number
RA856.4
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • IEEE Xplore
  • John Wiley & Sons
  • Institute of Electrical and Electronics Engineers
http://library.link/vocab/subjectName
  • Medical instruments and apparatus
  • Metal oxide semiconductors, Complementary
  • Medical instruments and apparatus
  • Metal oxide semiconductors, Complementary
Label
CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis, Yu Jiang, Nanyang Technological University, Singapore, Mei Yan, Illumina, US, Xiwei Huang, Hangzhou Dianzi University, China, Hao Yu, Nanyang Technological University, Singapore
Instantiates
Publication
Note
Made available via IEEE Xplore Digital Library
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Intro; Title Page; Copyright Page; Contents; Preface; Chapter 1 Introduction; 1.1 Personalized Biomedical Diagnosis; 1.1.1 Personalized Diagnosis; 1.1.2 Conventional Biomedical Diagnostic Instruments; 1.1.2.1 Optical Microscope; 1.1.2.2 Flow Cytometer; 1.1.2.3 DNA Sequencer; 1.2 CMOS Sensor-based Lab-on-a-Chip for System Miniaturization; 1.2.1 CMOS Sensor-based Lab-on-a-Chip; 1.2.2 CMOS Sensor; 1.2.2.1 CMOS Process Fundamentals; 1.2.2.2 CMOS Sensor Technology; 1.2.2.3 Multimodal CMOS Sensor; 1.2.3 Microfluidics; 1.2.3.1 Microfluidic Fundamentals; 1.2.3.2 Microfluidics Fabrication
  • 1.3 Objectives and Organization of this Book1.3.1 Objectives; 1.3.2 Organization; References; Chapter 2 CMOS Sensor Design; 2.1 Top Architecture; 2.2 Noise Overview; 2.2.1 Thermal Noise; 2.2.2 Flicker Noise; 2.2.3 Shot Noise; 2.2.4 MOSFET Noise Model; 2.3 Pixel Readout Circuit; 2.3.1 Source Follower; 2.3.2 Sub-threshold Gm Integrator; 2.3.3 CTIA; 2.4 Column Amplifier; 2.5 Column ADC; 2.5.1 Single-Slope ADC; 2.5.2 Sigma-Delta ADC; 2.6 Correlated Sampling; 2.6.1 Correlated Double Sampling; 2.6.2 Correlated Multiple Sampling; 2.7 Timing Control; 2.7.1 Row Timing Control
  • 2.7.2 Column Timing Control2.8 LVDS Interface; References; Chapter 3 CMOS Impedance Sensor; 3.1 Introduction; 3.2 CMOS Impedance Pixel; 3.3 Readout Circuit; 3.4 A 96 × 96 Electronic Impedance Sensing System; 3.4.1 Top Architecture; 3.4.2 System Implementation; 3.4.2.1 System Setup; 3.4.2.2 Sample Preparation; 3.4.3 Results; 3.4.3.1 Data Fitting for Single Cell Impedance Measurement; 3.4.3.2 Cell and Electrode Impedance Analysis; 3.4.3.3 EIS for Single-Cell Impedance Enumeration; References; Chapter 4 CMOS Terahertz Sensor; 4.1 Introduction; 4.2 CMOS THz Pixel
  • 4.2.1 Differential TL-SRR Resonator Design4.2.1.1 Stacked SRR Layout; 4.2.1.2 Comparison with Single-ended TL-SRR Resonator; 4.2.1.3 Comparison with Standing-Wave Resonator; 4.2.2 Differential TL-CSRR Resonator Design; 4.3 Readout Circuit; 4.3.1 Super-regenerative Amplification; 4.3.1.1 Equivalent Circuit of SRA; 4.3.1.2 Frequency Response of SRA; 4.3.1.3 Sensitivity of SRA; 4.3.2 Super-regenerative Receivers; 4.3.2.1 Quench-controlled Oscillation; 4.3.2.2 SRX Design by TL-CSRR; 4.3.2.3 SRX Design by TL-SRR; 4.4 A 135 GHz Imager; 4.4.1 135 GHz DTL-SRR-based Receiver
  • 4.4.2 System Implementation4.4.3 Results; 4.5 Plasmonic Sensor for Circulating Tumor Cell Detection; 4.5.1 Introduction of CTC Detection; 4.5.2 SRR-based Oscillator for CTC Detection; 4.5.3 Sensitivity of SRR-based Oscillator; References; Chapter 5 CMOS Ultrasound Sensor; 5.1 Introduction; 5.2 CMUT Pixel; 5.3 Readout Circuit; 5.4 A 320 × 320 CMUT-based Ultrasound Imaging System; 5.4.1 Top Architecture; 5.4.2 System Implementation; 5.4.2.1 Process Selection; 5.4.2.2 High Voltage Pulser; 5.4.2.3 Low-Noise Preamplifier and High Voltage Switch; 5.4.3 Results; 5.4.3.1 Simulation Results
Extent
1 online resource.
Form of item
online
Isbn
9781119218333
Lccn
2017050886
Media category
computer
Media MARC source
rdamedia
Media type code
n
Note
WorldCat record--MA
Specific material designation
remote
System control number
  • (OCoLC)1008762473
  • (OCoLC)on1008762473
Label
CMOS integrated lab-on-a-chip system for personalized biomedical diagnosis, Yu Jiang, Nanyang Technological University, Singapore, Mei Yan, Illumina, US, Xiwei Huang, Hangzhou Dianzi University, China, Hao Yu, Nanyang Technological University, Singapore
Publication
Note
Made available via IEEE Xplore Digital Library
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Intro; Title Page; Copyright Page; Contents; Preface; Chapter 1 Introduction; 1.1 Personalized Biomedical Diagnosis; 1.1.1 Personalized Diagnosis; 1.1.2 Conventional Biomedical Diagnostic Instruments; 1.1.2.1 Optical Microscope; 1.1.2.2 Flow Cytometer; 1.1.2.3 DNA Sequencer; 1.2 CMOS Sensor-based Lab-on-a-Chip for System Miniaturization; 1.2.1 CMOS Sensor-based Lab-on-a-Chip; 1.2.2 CMOS Sensor; 1.2.2.1 CMOS Process Fundamentals; 1.2.2.2 CMOS Sensor Technology; 1.2.2.3 Multimodal CMOS Sensor; 1.2.3 Microfluidics; 1.2.3.1 Microfluidic Fundamentals; 1.2.3.2 Microfluidics Fabrication
  • 1.3 Objectives and Organization of this Book1.3.1 Objectives; 1.3.2 Organization; References; Chapter 2 CMOS Sensor Design; 2.1 Top Architecture; 2.2 Noise Overview; 2.2.1 Thermal Noise; 2.2.2 Flicker Noise; 2.2.3 Shot Noise; 2.2.4 MOSFET Noise Model; 2.3 Pixel Readout Circuit; 2.3.1 Source Follower; 2.3.2 Sub-threshold Gm Integrator; 2.3.3 CTIA; 2.4 Column Amplifier; 2.5 Column ADC; 2.5.1 Single-Slope ADC; 2.5.2 Sigma-Delta ADC; 2.6 Correlated Sampling; 2.6.1 Correlated Double Sampling; 2.6.2 Correlated Multiple Sampling; 2.7 Timing Control; 2.7.1 Row Timing Control
  • 2.7.2 Column Timing Control2.8 LVDS Interface; References; Chapter 3 CMOS Impedance Sensor; 3.1 Introduction; 3.2 CMOS Impedance Pixel; 3.3 Readout Circuit; 3.4 A 96 × 96 Electronic Impedance Sensing System; 3.4.1 Top Architecture; 3.4.2 System Implementation; 3.4.2.1 System Setup; 3.4.2.2 Sample Preparation; 3.4.3 Results; 3.4.3.1 Data Fitting for Single Cell Impedance Measurement; 3.4.3.2 Cell and Electrode Impedance Analysis; 3.4.3.3 EIS for Single-Cell Impedance Enumeration; References; Chapter 4 CMOS Terahertz Sensor; 4.1 Introduction; 4.2 CMOS THz Pixel
  • 4.2.1 Differential TL-SRR Resonator Design4.2.1.1 Stacked SRR Layout; 4.2.1.2 Comparison with Single-ended TL-SRR Resonator; 4.2.1.3 Comparison with Standing-Wave Resonator; 4.2.2 Differential TL-CSRR Resonator Design; 4.3 Readout Circuit; 4.3.1 Super-regenerative Amplification; 4.3.1.1 Equivalent Circuit of SRA; 4.3.1.2 Frequency Response of SRA; 4.3.1.3 Sensitivity of SRA; 4.3.2 Super-regenerative Receivers; 4.3.2.1 Quench-controlled Oscillation; 4.3.2.2 SRX Design by TL-CSRR; 4.3.2.3 SRX Design by TL-SRR; 4.4 A 135 GHz Imager; 4.4.1 135 GHz DTL-SRR-based Receiver
  • 4.4.2 System Implementation4.4.3 Results; 4.5 Plasmonic Sensor for Circulating Tumor Cell Detection; 4.5.1 Introduction of CTC Detection; 4.5.2 SRR-based Oscillator for CTC Detection; 4.5.3 Sensitivity of SRR-based Oscillator; References; Chapter 5 CMOS Ultrasound Sensor; 5.1 Introduction; 5.2 CMUT Pixel; 5.3 Readout Circuit; 5.4 A 320 × 320 CMUT-based Ultrasound Imaging System; 5.4.1 Top Architecture; 5.4.2 System Implementation; 5.4.2.1 Process Selection; 5.4.2.2 High Voltage Pulser; 5.4.2.3 Low-Noise Preamplifier and High Voltage Switch; 5.4.3 Results; 5.4.3.1 Simulation Results
Extent
1 online resource.
Form of item
online
Isbn
9781119218333
Lccn
2017050886
Media category
computer
Media MARC source
rdamedia
Media type code
n
Note
WorldCat record--MA
Specific material designation
remote
System control number
  • (OCoLC)1008762473
  • (OCoLC)on1008762473

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