The Resource Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Stanford-UCSF Evidence-based Practice Center ; investigators, Dena M. Bravata ... [et al.], (electronic resource)

Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Stanford-UCSF Evidence-based Practice Center ; investigators, Dena M. Bravata ... [et al.], (electronic resource)

Label
Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease
Title
Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease
Statement of responsibility
prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Stanford-UCSF Evidence-based Practice Center ; investigators, Dena M. Bravata ... [et al.]
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
Atherosclerosis develops in a patchy, discontinuous fashion within coronary arteries. Therefore, it is possible to treat the discrete areas of obstruction that most impede coronary blood flow to the myocardium. The mechanical approaches to coronary revascularization fall broadly into two categories: coronary artery bypass grafting surgery (CABG) and catheter-based percutaneous coronary interventions (PCI). Together, these coronary revascularization methods are among the most common major medical procedures performed in North America and Europe. Coronary bypass surgery and coronary angioplasty (with or without stents) are alternative approaches to mechanical coronary revascularization, so their comparative effectiveness in terms of patient outcomes has been of great interest. The comparative effectiveness of bypass surgery and angioplasty is an open question primarily for those patients for whom either procedure would be technically feasible and whose coronary disease is neither too limited nor too extensive. CABG is generally preferred for patients with left main coronary artery disease or severe triple-vessel disease with reduced left ventricular function because it has been previously shown in randomized trials to improve survival compared with medical therapy. In contrast, PCI is generally preferred for patients with most forms of single-vessel disease when symptoms warrant coronary revascularization, in light of its lower procedural risk and the evidence that PCI reduces angina and myocardial ischemia in this subset of patients. The choice between PCI and CABG is most relevant for patients whose coronary artery disease (CAD) lies in between these extremes, namely patients with single-vessel disease of the proximal left anterior descending artery (LAD), most forms of double-vessel CAD, and less extensive forms of triple-vessel CAD. Most randomized controlled clinical trials (RCTs) of angioplasty and surgery have been conducted in this middle segment of the patient population with CAD. The purpose of this report is to evaluate the evidence for the comparative effectiveness of PCI and CABG in this population of patients with CAD
Member of
Cataloging source
DNLM
Funding information
Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services. 540 Gaither Road, Rockville, MD 20850. www.ahrq.gov Contract No. 290-02-0017. Prepared by:
Government publication
federal national government publication
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • statistics
NLM call number
WG 300
http://library.link/vocab/relatedWorkOrContributorName
  • Bravata, Dena M
  • United States
  • Stanford-UCSF Evidence-based Practice Center
Series statement
  • Comparative effectiveness review
  • AHRQ publication
  • AHRQ comparative effectiveness reviews
Series volume
  • no. 9
  • no. 08-EHC002-EF
http://library.link/vocab/subjectName
  • Coronary Artery Disease
  • Coronary Artery Bypass
  • Angioplasty
  • Treatment Outcome
  • United States
Label
Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Stanford-UCSF Evidence-based Practice Center ; investigators, Dena M. Bravata ... [et al.], (electronic resource)
Instantiates
Publication
Note
  • Title from PDF title page (viewed on June 13, 2011)
  • "October 2007."
  • "Contract No. 290-02-0017."
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource.
Form of item
online
Specific material designation
remote
System control number
  • 1559677
  • (DNLM)BKSHLF:NBK43032
Label
Comparative effectiveness of percutaneous coronary interventions and coronary artery bypass grafting for coronary artery disease, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by Stanford-UCSF Evidence-based Practice Center ; investigators, Dena M. Bravata ... [et al.], (electronic resource)
Publication
Note
  • Title from PDF title page (viewed on June 13, 2011)
  • "October 2007."
  • "Contract No. 290-02-0017."
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource.
Form of item
online
Specific material designation
remote
System control number
  • 1559677
  • (DNLM)BKSHLF:NBK43032

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