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The Resource Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
Resource Information
The item Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Boston University Libraries.This item is available to borrow from all library branches.
Resource Information
The item Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Boston University Libraries.
This item is available to borrow from all library branches.
 Summary
 The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as app
 Language

 eng
 eng
 Extent
 1 online resource (491 p.)
 Note
 Description based upon print version of record
 Contents

 Front Cover; Computer Methods, Part A; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators; 1. Introduction; Appendix I; Appendix II; Chapter 2: Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways; 2. Biochemical Conventions and Calculations; 3. Application to Physiological Systems; Chapter 3: Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes; 1. Introduction
 2. Decomposition of Sensor Errors3. Measures of Average Glycemia and Deviation from Target; 5. Measures and Plots of System Stability; 7. Conclusions; Chapter 4: Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing; 1. Introduction; 3. Job Submission; 5. Conclusions; Acknowledgments; Chapter 5: Discrete Stochastic Simulation Methods for Chemically Reacting Systems; 1. Introduction; 2. The Chemical Master Equation; 3. The Stochastic Simulation Algorithm; 5. Measurement of Simulation Error
 Chapter 6: Analyses for Physiological and Behavioral Rhythmicity1. Introduction; 2. Types of Biological Data and their Acquisition; 5. Time/Frequency Analysis and the Wavelet Transform; 7. Strength and Regularity of a Signal; 8. Conclusions; References; Chapter 7: A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface ChargeCharge Interactions; 1. Introduction; 2. Computational Design of Surface ChargeCharge Interactions; Acknowledgments; References
 Chapter 8: Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space1. Introduction; 2. Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region; 3. Approximating a OneDimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces; 6. An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
 Chapter 9: Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using StructureBased pKa Calculations and Titration Curve Fitting3. Setting up and Running a pKa Calculation; 5. How Reliable are Calculated pKa Values?; 6. Predicting pH Activity Profiles; References; Chapter 10: Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances; 1. Introduction; 2. Review of Least Squares; 3. Experiment Design Using Vprior  Numerical Illustrations; References; Chapter 11: Evaluation and Comparison of Computational Models; 1. Introduction; 3. Model Comparison Methods
 Acknowledgments
 Isbn
 9781282285644
 Label
 Computer methods, Part A
 Title
 Computer methods
 Title part
 Part A
 Statement of responsibility
 edited by Michael L. Johnson, Ludwig Brand
 Language

 eng
 eng
 Summary
 The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as app
 Cataloging source
 MiAaPQ
 Dewey number

 610.28
 610.727
 Illustrations
 illustrations
 Index
 index present
 Language note
 English
 LC call number
 QP601
 LC item number
 .C66A 2009
 Literary form
 non fiction
 Nature of contents

 dictionaries
 bibliography
 http://library.link/vocab/relatedWorkOrContributorDate
 1947
 http://library.link/vocab/relatedWorkOrContributorName

 Johnson, Michael L.
 Brand, Ludwig
 Series statement
 Methods in enzymology
 Series volume
 454
 http://library.link/vocab/subjectName

 Biomedical engineering
 Enzymology
 Label
 Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
 Note
 Description based upon print version of record
 Bibliography note
 Includes bibliographical references and index
 Carrier category
 online resource
 Carrier category code

 cr
 Content category
 text
 Content type code

 txt
 Contents

 Front Cover; Computer Methods, Part A; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators; 1. Introduction; Appendix I; Appendix II; Chapter 2: Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways; 2. Biochemical Conventions and Calculations; 3. Application to Physiological Systems; Chapter 3: Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes; 1. Introduction
 2. Decomposition of Sensor Errors3. Measures of Average Glycemia and Deviation from Target; 5. Measures and Plots of System Stability; 7. Conclusions; Chapter 4: Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing; 1. Introduction; 3. Job Submission; 5. Conclusions; Acknowledgments; Chapter 5: Discrete Stochastic Simulation Methods for Chemically Reacting Systems; 1. Introduction; 2. The Chemical Master Equation; 3. The Stochastic Simulation Algorithm; 5. Measurement of Simulation Error
 Chapter 6: Analyses for Physiological and Behavioral Rhythmicity1. Introduction; 2. Types of Biological Data and their Acquisition; 5. Time/Frequency Analysis and the Wavelet Transform; 7. Strength and Regularity of a Signal; 8. Conclusions; References; Chapter 7: A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface ChargeCharge Interactions; 1. Introduction; 2. Computational Design of Surface ChargeCharge Interactions; Acknowledgments; References
 Chapter 8: Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space1. Introduction; 2. Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region; 3. Approximating a OneDimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces; 6. An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
 Chapter 9: Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using StructureBased pKa Calculations and Titration Curve Fitting3. Setting up and Running a pKa Calculation; 5. How Reliable are Calculated pKa Values?; 6. Predicting pH Activity Profiles; References; Chapter 10: Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances; 1. Introduction; 2. Review of Least Squares; 3. Experiment Design Using Vprior  Numerical Illustrations; References; Chapter 11: Evaluation and Comparison of Computational Models; 1. Introduction; 3. Model Comparison Methods
 Acknowledgments
 Dimensions
 unknown
 Extent
 1 online resource (491 p.)
 Form of item
 online
 Isbn
 9781282285644
 Media category
 computer
 Media type code

 c
 Specific material designation
 remote
 System control number

 (EBL)452850
 (OCoLC)302408753
 (SSID)ssj0000292362
 (PQKBManifestationID)12068779
 (PQKBTitleCode)TC0000292362
 (PQKBWorkID)10268941
 (PQKB)11514710
 (MiAaPQ)EBC452850
 (EXLCZ)991000000000790418
 Label
 Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
 Note
 Description based upon print version of record
 Bibliography note
 Includes bibliographical references and index
 Carrier category
 online resource
 Carrier category code

 cr
 Content category
 text
 Content type code

 txt
 Contents

 Front Cover; Computer Methods, Part A; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators; 1. Introduction; Appendix I; Appendix II; Chapter 2: Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways; 2. Biochemical Conventions and Calculations; 3. Application to Physiological Systems; Chapter 3: Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes; 1. Introduction
 2. Decomposition of Sensor Errors3. Measures of Average Glycemia and Deviation from Target; 5. Measures and Plots of System Stability; 7. Conclusions; Chapter 4: Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing; 1. Introduction; 3. Job Submission; 5. Conclusions; Acknowledgments; Chapter 5: Discrete Stochastic Simulation Methods for Chemically Reacting Systems; 1. Introduction; 2. The Chemical Master Equation; 3. The Stochastic Simulation Algorithm; 5. Measurement of Simulation Error
 Chapter 6: Analyses for Physiological and Behavioral Rhythmicity1. Introduction; 2. Types of Biological Data and their Acquisition; 5. Time/Frequency Analysis and the Wavelet Transform; 7. Strength and Regularity of a Signal; 8. Conclusions; References; Chapter 7: A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface ChargeCharge Interactions; 1. Introduction; 2. Computational Design of Surface ChargeCharge Interactions; Acknowledgments; References
 Chapter 8: Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space1. Introduction; 2. Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region; 3. Approximating a OneDimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces; 6. An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
 Chapter 9: Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using StructureBased pKa Calculations and Titration Curve Fitting3. Setting up and Running a pKa Calculation; 5. How Reliable are Calculated pKa Values?; 6. Predicting pH Activity Profiles; References; Chapter 10: Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances; 1. Introduction; 2. Review of Least Squares; 3. Experiment Design Using Vprior  Numerical Illustrations; References; Chapter 11: Evaluation and Comparison of Computational Models; 1. Introduction; 3. Model Comparison Methods
 Acknowledgments
 Dimensions
 unknown
 Extent
 1 online resource (491 p.)
 Form of item
 online
 Isbn
 9781282285644
 Media category
 computer
 Media type code

 c
 Specific material designation
 remote
 System control number

 (EBL)452850
 (OCoLC)302408753
 (SSID)ssj0000292362
 (PQKBManifestationID)12068779
 (PQKBTitleCode)TC0000292362
 (PQKBWorkID)10268941
 (PQKB)11514710
 (MiAaPQ)EBC452850
 (EXLCZ)991000000000790418
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