The Resource Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)

Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)

Label
Computer methods, Part A
Title
Computer methods
Title part
Part A
Statement of responsibility
edited by Michael L. Johnson, Ludwig Brand
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as app
Member of
Is Subseries of
Cataloging source
MiAaPQ
Dewey number
  • 610.28
  • 610.727
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QP601
LC item number
.C66A 2009
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorDate
1947-
http://library.link/vocab/relatedWorkOrContributorName
  • Johnson, Michael L.
  • Brand, Ludwig
Series statement
Methods in enzymology
Series volume
454
http://library.link/vocab/subjectName
  • Biomedical engineering
  • Enzymology
Label
Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
  • Front Cover; Computer Methods, Part A; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators; 1. Introduction; Appendix I; Appendix II; Chapter 2: Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways; 2. Biochemical Conventions and Calculations; 3. Application to Physiological Systems; Chapter 3: Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes; 1. Introduction
  • 2. Decomposition of Sensor Errors3. Measures of Average Glycemia and Deviation from Target; 5. Measures and Plots of System Stability; 7. Conclusions; Chapter 4: Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing; 1. Introduction; 3. Job Submission; 5. Conclusions; Acknowledgments; Chapter 5: Discrete Stochastic Simulation Methods for Chemically Reacting Systems; 1. Introduction; 2. The Chemical Master Equation; 3. The Stochastic Simulation Algorithm; 5. Measurement of Simulation Error
  • Chapter 6: Analyses for Physiological and Behavioral Rhythmicity1. Introduction; 2. Types of Biological Data and their Acquisition; 5. Time/Frequency Analysis and the Wavelet Transform; 7. Strength and Regularity of a Signal; 8. Conclusions; References; Chapter 7: A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface Charge-Charge Interactions; 1. Introduction; 2. Computational Design of Surface Charge-Charge Interactions; Acknowledgments; References
  • Chapter 8: Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space1. Introduction; 2. Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region; 3. Approximating a One-Dimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces; 6. An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
  • Chapter 9: Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using Structure-Based pKa Calculations and Titration Curve Fitting3. Setting up and Running a pKa Calculation; 5. How Reliable are Calculated pKa Values?; 6. Predicting pH Activity Profiles; References; Chapter 10: Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances; 1. Introduction; 2. Review of Least Squares; 3. Experiment Design Using Vprior - Numerical Illustrations; References; Chapter 11: Evaluation and Comparison of Computational Models; 1. Introduction; 3. Model Comparison Methods
  • Acknowledgments
Dimensions
unknown
Extent
1 online resource (491 p.)
Form of item
online
Isbn
9781282285644
Media category
computer
Media type code
  • c
Specific material designation
remote
System control number
  • (EBL)452850
  • (OCoLC)302408753
  • (SSID)ssj0000292362
  • (PQKBManifestationID)12068779
  • (PQKBTitleCode)TC0000292362
  • (PQKBWorkID)10268941
  • (PQKB)11514710
  • (MiAaPQ)EBC452850
  • (EXLCZ)991000000000790418
Label
Computer methods, Part A, edited by Michael L. Johnson, Ludwig Brand, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
  • Front Cover; Computer Methods, Part A; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators; 1. Introduction; Appendix I; Appendix II; Chapter 2: Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways; 2. Biochemical Conventions and Calculations; 3. Application to Physiological Systems; Chapter 3: Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes; 1. Introduction
  • 2. Decomposition of Sensor Errors3. Measures of Average Glycemia and Deviation from Target; 5. Measures and Plots of System Stability; 7. Conclusions; Chapter 4: Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing; 1. Introduction; 3. Job Submission; 5. Conclusions; Acknowledgments; Chapter 5: Discrete Stochastic Simulation Methods for Chemically Reacting Systems; 1. Introduction; 2. The Chemical Master Equation; 3. The Stochastic Simulation Algorithm; 5. Measurement of Simulation Error
  • Chapter 6: Analyses for Physiological and Behavioral Rhythmicity1. Introduction; 2. Types of Biological Data and their Acquisition; 5. Time/Frequency Analysis and the Wavelet Transform; 7. Strength and Regularity of a Signal; 8. Conclusions; References; Chapter 7: A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface Charge-Charge Interactions; 1. Introduction; 2. Computational Design of Surface Charge-Charge Interactions; Acknowledgments; References
  • Chapter 8: Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space1. Introduction; 2. Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region; 3. Approximating a One-Dimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces; 6. An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
  • Chapter 9: Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using Structure-Based pKa Calculations and Titration Curve Fitting3. Setting up and Running a pKa Calculation; 5. How Reliable are Calculated pKa Values?; 6. Predicting pH Activity Profiles; References; Chapter 10: Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances; 1. Introduction; 2. Review of Least Squares; 3. Experiment Design Using Vprior - Numerical Illustrations; References; Chapter 11: Evaluation and Comparison of Computational Models; 1. Introduction; 3. Model Comparison Methods
  • Acknowledgments
Dimensions
unknown
Extent
1 online resource (491 p.)
Form of item
online
Isbn
9781282285644
Media category
computer
Media type code
  • c
Specific material designation
remote
System control number
  • (EBL)452850
  • (OCoLC)302408753
  • (SSID)ssj0000292362
  • (PQKBManifestationID)12068779
  • (PQKBTitleCode)TC0000292362
  • (PQKBWorkID)10268941
  • (PQKB)11514710
  • (MiAaPQ)EBC452850
  • (EXLCZ)991000000000790418

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