The Resource Cystogenesis, edited by Jong Hoon Park, Curie Ahn, (electronic resource)

Cystogenesis, edited by Jong Hoon Park, Curie Ahn, (electronic resource)

Label
Cystogenesis
Title
Cystogenesis
Statement of responsibility
edited by Jong Hoon Park, Curie Ahn
Contributor
Editor
Provider
Subject
Language
eng
Summary
This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine
Member of
Image bit depth
0
LC call number
  • RB155-155.8
  • QH431
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Park, Jong Hoon.
  • Ahn, Curie.
  • SpringerLink
Series statement
Advances in Experimental Medicine and Biology,
Series volume
933
http://library.link/vocab/subjectName
  • Medicine
  • Human genetics
  • Medical microbiology
  • Molecular biology
  • Cell biology
  • Biomedicine
  • Human Genetics
  • Molecular Medicine
  • Cell Biology
  • Medical Microbiology
Label
Cystogenesis, edited by Jong Hoon Park, Curie Ahn, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD
Dimensions
unknown
Extent
IX, 126 p.
File format
multiple file formats
Form of item
electronic
Isbn
9789811020414
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-981-10-2041-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-981-10-2041-4
Label
Cystogenesis, edited by Jong Hoon Park, Curie Ahn, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD
Dimensions
unknown
Extent
IX, 126 p.
File format
multiple file formats
Form of item
electronic
Isbn
9789811020414
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-981-10-2041-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-981-10-2041-4

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