The Resource DNA Arrays in Neurobiology, (electronic resource)

DNA Arrays in Neurobiology, (electronic resource)

Label
DNA Arrays in Neurobiology
Title
DNA Arrays in Neurobiology
Title variation
  • International Review of Neurobiology
  • International Review of Neurobiology, Volume 60C
  • DNA Arrays in Neurobiology , Volume 60C
Creator
Contributor
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
DNA array technology is a technique for studying gene expression by comparing samples of different genes. The result is an enormous amount of data that must be carefully analyzed in order for it to be useful and meaningful. This book examines both data analysis and techniques for ensuring optimal experimental conditions. The array approach has applications in a number of model systems, including development, learning and drug abuse. In addition, the technique has applications in a number of neurological disorders such as Alzheimer's disease, schizophrenia, multiple sclerosis, and neurological
Member of
Is Subseries of
Cataloging source
AU-PeEL
http://library.link/vocab/creatorName
Miles, Michael
Dewey number
572.8633
Language note
English
LC call number
QP624.5.D726 D19 2004eb
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Miles, Michael F
Series statement
International review of neurobiology
http://library.link/vocab/subjectName
  • DNA microarrays
  • Neurobiology
  • Oligonucleotide Array Sequence Analysis
  • Nucleic Acid Hybridization
  • Sequence Analysis
  • Neurosciences
  • Molecular Probe Techniques
  • Microarray Analysis
  • Genetic Techniques
  • Biology
  • Biological Science Disciplines
  • Microchip Analytical Procedures
  • Investigative Techniques
  • Analytical, Diagnostic and Therapeutic Techniques and Equipment
  • Natural Science Disciplines
  • Chemistry Techniques, Analytical
  • Disciplines and Occupations
  • Gene Expression Profiling
  • Oligonucleotide Array Sequence Analysis
  • Neurobiology
  • Medicine
  • Health & Biological Sciences
  • Neurology
Label
DNA Arrays in Neurobiology, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Abbreviated title
DNA ARRAYS IN NEUROBIOLOGY
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
  • Cover; Contents; Contributors; Introduction; Chapter 1. Microarray Platforms: Introduction and Application to Neurobiology; I. Introduction; II. Experimental Flow; III. Microarray Design; IV. Slides and Probes; V. Sample Preparation and Labeling; VI. Data Analysis; VII. Data Interpretation; VIII. Confirmation of Microarray Results; IX. Conclusion; X. Online Resources; References; Chapter 2. Experimental Design and Low-Level Analysis of Microarray Data; I. Introduction; II. Design of Experiments; III. Sample Size Considerations; IV. Normalization; V. Expression Summaries for GeneChip Data
  • VI. Quality AssessmentVII. Detection of Absolute Gene Expression; References; Chapter 3. Brain Gene Expression: Genomics and Genetics; I. Introduction; II. Transcript Abundance as a Complex Trait; III. Genetic Dissection of Transcription Regulation; IV. How Many QTLs Are There? Statistical Control in Two Dimensions; V. Probe Versus Probe Set-Level Phenotypes; VI. Transcription Regulatory Networks; VII. Functional Correlates of Brain Transcriptional Activity; VIII. Conclusions: Building a Model of Brain Function from Multipoint, Multi-tissue Gene Expression, and Phenomic Observation
  • ReferencesChapter 4. DNA Microarrays and Animal Models of Learning and Memory; I. Introduction; II. DNA Microarray Technology; III. Use of DNA Microarrays for Studying Learning and Memory; IV. Conclusion; References; Chapter 5. Microarray Analysis of Human Nervous System Gene Expression in Neurological Disease; I. Introduction; II. Disease Pathophysiology; III. Microarray-Based Disease Classification; IV. Human Neurological Diseases Studied by Microarray Technology; V. Conclusion; References; Chapter 6. DNA Microarray Analysis of Postmortem Brain Tissue; I. Introduction
  • II. Challenges in Studies of the Postmortem Human BrainIII. Microarray Analysis of Human Brain Disorders; IV. Where Do We Go from Here?; References; Index; Contents of Recent Volumes
Dimensions
unknown
Extent
1 online resource (218 p.)
Form of item
electronic
Isbn
9780080495514
Media category
computer
Media type code
  • c
Specific material designation
remote
System control number
  • (EBL)296976
  • (OCoLC)469606895
  • (SSID)ssj0000140396
  • (PQKBManifestationID)11159905
  • (PQKBTitleCode)TC0000140396
  • (PQKBWorkID)10052681
  • (PQKB)10602586
  • (EXLCZ)991000000000364201
Label
DNA Arrays in Neurobiology, (electronic resource)
Publication
Note
Description based upon print version of record
Abbreviated title
DNA ARRAYS IN NEUROBIOLOGY
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
  • Cover; Contents; Contributors; Introduction; Chapter 1. Microarray Platforms: Introduction and Application to Neurobiology; I. Introduction; II. Experimental Flow; III. Microarray Design; IV. Slides and Probes; V. Sample Preparation and Labeling; VI. Data Analysis; VII. Data Interpretation; VIII. Confirmation of Microarray Results; IX. Conclusion; X. Online Resources; References; Chapter 2. Experimental Design and Low-Level Analysis of Microarray Data; I. Introduction; II. Design of Experiments; III. Sample Size Considerations; IV. Normalization; V. Expression Summaries for GeneChip Data
  • VI. Quality AssessmentVII. Detection of Absolute Gene Expression; References; Chapter 3. Brain Gene Expression: Genomics and Genetics; I. Introduction; II. Transcript Abundance as a Complex Trait; III. Genetic Dissection of Transcription Regulation; IV. How Many QTLs Are There? Statistical Control in Two Dimensions; V. Probe Versus Probe Set-Level Phenotypes; VI. Transcription Regulatory Networks; VII. Functional Correlates of Brain Transcriptional Activity; VIII. Conclusions: Building a Model of Brain Function from Multipoint, Multi-tissue Gene Expression, and Phenomic Observation
  • ReferencesChapter 4. DNA Microarrays and Animal Models of Learning and Memory; I. Introduction; II. DNA Microarray Technology; III. Use of DNA Microarrays for Studying Learning and Memory; IV. Conclusion; References; Chapter 5. Microarray Analysis of Human Nervous System Gene Expression in Neurological Disease; I. Introduction; II. Disease Pathophysiology; III. Microarray-Based Disease Classification; IV. Human Neurological Diseases Studied by Microarray Technology; V. Conclusion; References; Chapter 6. DNA Microarray Analysis of Postmortem Brain Tissue; I. Introduction
  • II. Challenges in Studies of the Postmortem Human BrainIII. Microarray Analysis of Human Brain Disorders; IV. Where Do We Go from Here?; References; Index; Contents of Recent Volumes
Dimensions
unknown
Extent
1 online resource (218 p.)
Form of item
electronic
Isbn
9780080495514
Media category
computer
Media type code
  • c
Specific material designation
remote
System control number
  • (EBL)296976
  • (OCoLC)469606895
  • (SSID)ssj0000140396
  • (PQKBManifestationID)11159905
  • (PQKBTitleCode)TC0000140396
  • (PQKBWorkID)10052681
  • (PQKB)10602586
  • (EXLCZ)991000000000364201

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