The Resource ECTO-NOX Proteins : Growth, Cancer, and Aging, by D. James Morré, Dorothy M. Morré, (electronic resource)

ECTO-NOX Proteins : Growth, Cancer, and Aging, by D. James Morré, Dorothy M. Morré, (electronic resource)

Label
ECTO-NOX Proteins : Growth, Cancer, and Aging
Title
ECTO-NOX Proteins
Title remainder
Growth, Cancer, and Aging
Statement of responsibility
by D. James Morré, Dorothy M. Morré
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
"ENOX Proteins" documents a unique family of cell surface proteins which are the exclusive discovery (subsequently confirmed by others) of the authors, their students and their colleagues. An ENOX-based mechanism is provided for how cells increase in size that is both unique and applicable not only to cancer and cancer therapy but also to production agriculture and biomass increase. The role of ENOX proteins in biological time-keeping is described along with evidence for oscillations in the ratios of electron spin pairs defining ortho and para water states that form highly coordinated populations of coherent water of interest to physicists as the underlying mechanism. The age-related NADH oxidases that appear around age 30 and increase steadily thereafter with potentially causal involvements in atherogenesis and skin aging have been identified as five members of the TM-9 protein superfamily of all with different chromosomal locations. The arNOX proteins initially are membrane anchored but functionally-active N-terminal fragments that are shed into body fluids. Except for critical functional motifs, all of the ENOX protein family members have distinct protein sequences and chromosomal origins. A fourth member of the ENOX protein family occurs in plants as the primary target for both natural and synthetic growth hormone (auxin)-stimulated rapid cell enlargement. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins offer remarkable opportunities for research, commercial development and outside confirmation of new paradigms to help explain complex biological processes
http://library.link/vocab/creatorName
Morré, D. James
Image bit depth
0
LC call number
QD431-431.7
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Morré, Dorothy M.
  • SpringerLink
http://library.link/vocab/subjectName
  • Life sciences
  • Oncology
  • Biochemistry
  • Proteomics
  • Cytokines
  • Cytology
  • Life Sciences
  • Protein Science
  • Proteomics
  • Cell Biology
  • Cytokines and Growth Factors
  • Cancer Research
  • Plant Biochemistry
Label
ECTO-NOX Proteins : Growth, Cancer, and Aging, by D. James Morré, Dorothy M. Morré, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preface -- The ECTO-NOX protein family -- Measurement of ECTO-NOX (ENOX) activities -- The constitutive ENOX1 (CNOX) -- Role in plasma membrane electron transport -- Role in the enlargement phase of cell growth -- Role as ultradian oscillators of the cells’ biological clock -- Other potential functional roles of ENOX proteins -- ENOX2 (tNOX) and cancer -- Age-related ENOX proteins (arNOX) -- The auxin-stimulated ENOX and auxin-stimulation of plant growth -- Cancer therapeutic applications of ENOX2 proteins -- Diagnostic applicastions of ENOX2 proteins -- Appendix A Epilogue: Remaining challenges -- Appendix B Detailed description of 2-D gel electrophoresis western blot early detection protocol
Dimensions
unknown
Extent
XVI, 507 p. 281 illus., 13 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9781461439585
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-4614-3958-5
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-4614-3958-5
Label
ECTO-NOX Proteins : Growth, Cancer, and Aging, by D. James Morré, Dorothy M. Morré, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preface -- The ECTO-NOX protein family -- Measurement of ECTO-NOX (ENOX) activities -- The constitutive ENOX1 (CNOX) -- Role in plasma membrane electron transport -- Role in the enlargement phase of cell growth -- Role as ultradian oscillators of the cells’ biological clock -- Other potential functional roles of ENOX proteins -- ENOX2 (tNOX) and cancer -- Age-related ENOX proteins (arNOX) -- The auxin-stimulated ENOX and auxin-stimulation of plant growth -- Cancer therapeutic applications of ENOX2 proteins -- Diagnostic applicastions of ENOX2 proteins -- Appendix A Epilogue: Remaining challenges -- Appendix B Detailed description of 2-D gel electrophoresis western blot early detection protocol
Dimensions
unknown
Extent
XVI, 507 p. 281 illus., 13 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9781461439585
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-4614-3958-5
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-4614-3958-5

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