The Resource Hedgehog-Gli Signaling in Human Disease, by Ariel Ruiz i Altaba, (electronic resource)

Hedgehog-Gli Signaling in Human Disease, by Ariel Ruiz i Altaba, (electronic resource)

Label
Hedgehog-Gli Signaling in Human Disease
Title
Hedgehog-Gli Signaling in Human Disease
Statement of responsibility
by Ariel Ruiz i Altaba
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies
Member of
http://library.link/vocab/creatorName
Ruiz i Altaba, Ariel
Image bit depth
0
LC call number
RC261-271
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
SpringerLink
Series statement
Molecular Biology Intelligence Unit
http://library.link/vocab/subjectName
  • Medicine
  • Oncology
  • Human genetics
  • Developmental biology
  • Biomedicine
  • Cancer Research
  • Developmental Biology
  • Human Genetics
Label
Hedgehog-Gli Signaling in Human Disease, by Ariel Ruiz i Altaba, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
How the Hedgehog Outfoxed the Crab -- The Patched Receptor -- Making a Morphogenetic Gradient -- Spatial and Temporal Regulation of Hair Follicle Progenitors by Hedgehog Signaling -- Mode of PTCH1/Ptch1-Associated Tumor Formation -- Basal Cell Carcinomas, Hedgehog Signaling, and the Ptch1+/- Mouse -- GLI Genes and Their Targets in Epidermal Development and Disease -- Splitting Hairs -- Shh Expression in Pulmonary Injury and Disease -- Human Correlates of GLI3 Function -- From Oligodactyly to Polydactyly -- The Genetics of Indian Hedgehog -- Sonic Hedgehog Signaling in Craniofacial Development -- Important Role of Shh Controlling Gli3 Functions during the Dorsal-Ventral Patterning of the Telencephalon -- Regulation of Early Events in Cell Cycle Progression by Hedgehog Signaling in CNS Development and Tumorigenesis -- Modulating the Hedgehog Pathway in Diseases -- Hedgehog Signaling in Endodermally Derived Tumors
Dimensions
unknown
Extent
XI, 228 p.
File format
multiple file formats
Form of item
electronic
Isbn
9780387337777
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/0-387-33777-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-0-387-33777-7
Label
Hedgehog-Gli Signaling in Human Disease, by Ariel Ruiz i Altaba, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
How the Hedgehog Outfoxed the Crab -- The Patched Receptor -- Making a Morphogenetic Gradient -- Spatial and Temporal Regulation of Hair Follicle Progenitors by Hedgehog Signaling -- Mode of PTCH1/Ptch1-Associated Tumor Formation -- Basal Cell Carcinomas, Hedgehog Signaling, and the Ptch1+/- Mouse -- GLI Genes and Their Targets in Epidermal Development and Disease -- Splitting Hairs -- Shh Expression in Pulmonary Injury and Disease -- Human Correlates of GLI3 Function -- From Oligodactyly to Polydactyly -- The Genetics of Indian Hedgehog -- Sonic Hedgehog Signaling in Craniofacial Development -- Important Role of Shh Controlling Gli3 Functions during the Dorsal-Ventral Patterning of the Telencephalon -- Regulation of Early Events in Cell Cycle Progression by Hedgehog Signaling in CNS Development and Tumorigenesis -- Modulating the Hedgehog Pathway in Diseases -- Hedgehog Signaling in Endodermally Derived Tumors
Dimensions
unknown
Extent
XI, 228 p.
File format
multiple file formats
Form of item
electronic
Isbn
9780387337777
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/0-387-33777-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-0-387-33777-7

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