The Resource Hormones, Intrauterine Health and Programming, edited by Jonathan R Seckl, Yves Christen, (electronic resource)

Hormones, Intrauterine Health and Programming, edited by Jonathan R Seckl, Yves Christen, (electronic resource)

Label
Hormones, Intrauterine Health and Programming
Title
Hormones, Intrauterine Health and Programming
Statement of responsibility
edited by Jonathan R Seckl, Yves Christen
Creator
Contributor
Editor
Provider
Subject
Language
eng
Summary
The environment of the fetus in the womb is emerging as a key determinant not only of its immediate status but also of the offspring’s long-term well-being. This largely started with reports of striking epidemiological associations between lower, but still normal, birth weight and a marked increase in the incidence of cardiac, metabolic and neuropsychiatric disorders from childhood to senescence. In seeking to explain these observations, collectively referred to as ‘developmental programming,’ a new subfield of biology has emerged. Major discoveries include detailing the etiological roles of maternal factors such as nutrition, inflammatory disease, stress and psychopathology. Key biochemical mediators have been discovered, notably including hormones such as glucocorticoids, which act on both the fetus and the placenta to change the trajectory of growth, tissue maturation and the expression of specific genes in affected cells. Such persisting changes in the transcription of genes may be in part underpinned by epigenetic changes. The mechanisms of these effects are beginning to emerge and offer the prospect of new diagnostics, biomarkers and potential therapeutic targets. This work provides an accessible and cutting-edge view of this rapidly emerging field
Member of
http://library.link/vocab/creatorName
Seckl, Jonathan R
Image bit depth
0
LC call number
  • RB155-155.8
  • QH431
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Christen, Yves.
  • SpringerLink
Series statement
Research and Perspectives in Endocrine Interactions,
Series volume
12
http://library.link/vocab/subjectName
  • Medicine
  • Human genetics
  • Obstetrics
  • Endocrinology
  • Biomedicine
  • Human Genetics
  • Endocrinology
  • Obstetrics/Perinatology
Label
Hormones, Intrauterine Health and Programming, edited by Jonathan R Seckl, Yves Christen, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Foreword -- Early growth and later health: findings from the Helsinki Birth Cohort Study by Johan G. Eriksson -- Male and female placentas have divergent transcriptomic and epigenomic responses to maternal diets: not just hormones by Anne Gabory, Alexandre Vigé, Jean Lesage, Isabelle Fajardy, Laure Ferry, Linda Attig, Anne Vambergue, Didier Vieau, Jean-Philippe Jais, Luc Jouneau, and Claudine Junien -- Glucocorticoids and fetal programming; necessary and sufficient? By Jonathan R. Seckl -- Developmental programming and the placenta: focusing in on glucocorticoids by Caitlin S. Wyrwoll -- Maternal stress and in utero programming by Louise C. Kenny, Claire Everard and Ali S. Khashan -- Developmental epigenetics and risks of later non-communicable disease by M.A. Hanson, P.D. Gluckman and K.M. Godfrey -- Epigenetic effects of extreme intrauterine growth in humans by John M. Greally -- The Role of the Placenta in Fetal Programming by John Challis, Debora Sloboda, Shaofu Li, Thorsten Braun, Frank Bloomfield, Ghazala Begum, Anne White, Felice Petraglia, John Newnham -- Developmental Origins of Diabetes: The Role of Epigenetics by Rebecca A. Simmons -- Glucocorticoids, programming and the transmission of effects across generations by Amanda J. Drake -- Subject index
Dimensions
unknown
Extent
XIV, 189 p. 10 illus., 9 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319025919
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-02591-9
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-02591-9
Label
Hormones, Intrauterine Health and Programming, edited by Jonathan R Seckl, Yves Christen, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Foreword -- Early growth and later health: findings from the Helsinki Birth Cohort Study by Johan G. Eriksson -- Male and female placentas have divergent transcriptomic and epigenomic responses to maternal diets: not just hormones by Anne Gabory, Alexandre Vigé, Jean Lesage, Isabelle Fajardy, Laure Ferry, Linda Attig, Anne Vambergue, Didier Vieau, Jean-Philippe Jais, Luc Jouneau, and Claudine Junien -- Glucocorticoids and fetal programming; necessary and sufficient? By Jonathan R. Seckl -- Developmental programming and the placenta: focusing in on glucocorticoids by Caitlin S. Wyrwoll -- Maternal stress and in utero programming by Louise C. Kenny, Claire Everard and Ali S. Khashan -- Developmental epigenetics and risks of later non-communicable disease by M.A. Hanson, P.D. Gluckman and K.M. Godfrey -- Epigenetic effects of extreme intrauterine growth in humans by John M. Greally -- The Role of the Placenta in Fetal Programming by John Challis, Debora Sloboda, Shaofu Li, Thorsten Braun, Frank Bloomfield, Ghazala Begum, Anne White, Felice Petraglia, John Newnham -- Developmental Origins of Diabetes: The Role of Epigenetics by Rebecca A. Simmons -- Glucocorticoids, programming and the transmission of effects across generations by Amanda J. Drake -- Subject index
Dimensions
unknown
Extent
XIV, 189 p. 10 illus., 9 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319025919
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-02591-9
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-02591-9

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