The Resource Immune Metabolism in Health and Tumor, edited by Bin Li, Fan Pan, (electronic resource)

Immune Metabolism in Health and Tumor, edited by Bin Li, Fan Pan, (electronic resource)

Label
Immune Metabolism in Health and Tumor
Title
Immune Metabolism in Health and Tumor
Statement of responsibility
edited by Bin Li, Fan Pan
Contributor
Editor
Provider
Subject
Language
eng
Summary
This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients. The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of these pathways can lead to immune disorders. In different contexts, such as a tumor microenvironment, immune-cell function and identity may be modified not only by cytokines and checkpoint molecules, but also by nutrient availability and other metabolic stimuli. Transcriptional reprogramming confers many of the changes in immune cell metabolism that are seen when a T-cell, for example, undergoes activation or functional adaptation to different environments. Lastly, immune cells can destructively or protectively participate in human metabolic homeostasis or disorders. This book summarizes immune-metabolism from a variety of different perspectives, including the ways in which metabolic cues, pathways, and requirements of immune cells change in conditions of homeostasis and activation. The exploration of the significance of metabolic checkpoints and other cues, particularly in the context of cancer and immune disorders, may form the foundation for the development of therapeutics
Member of
Image bit depth
0
LC call number
QR180-189.5
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Li, Bin.
  • Pan, Fan.
  • SpringerLink
Series statement
Advances in Experimental Medicine and Biology,
Series volume
1011
http://library.link/vocab/subjectName
  • Medicine
  • Cancer
  • Immunology
  • Medical microbiology
  • Post-translational modification
  • Biomedicine
  • Immunology
  • Posttranslational Modification
  • Medical Microbiology
  • Cancer Research
Label
Immune Metabolism in Health and Tumor, edited by Bin Li, Fan Pan, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Metabolism in Immune Cell Differentiation and Function -- Metabolic Regulation of T cell Immunity -- Transcriptional regulation of T cell metabolism reprograming -- Adipose tissue-resident regulatory T cells -- Immune cell metabolism in tumor microenvironment -- Regulation of Metabolism across Different Subsets of T Cells in Cancer -- Immunometabolism in Tumour Microenvironment
Dimensions
unknown
Extent
V, 223 p. 24 illus., 23 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789402411706
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-94-024-1170-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-94-024-1170-6
Label
Immune Metabolism in Health and Tumor, edited by Bin Li, Fan Pan, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Metabolism in Immune Cell Differentiation and Function -- Metabolic Regulation of T cell Immunity -- Transcriptional regulation of T cell metabolism reprograming -- Adipose tissue-resident regulatory T cells -- Immune cell metabolism in tumor microenvironment -- Regulation of Metabolism across Different Subsets of T Cells in Cancer -- Immunometabolism in Tumour Microenvironment
Dimensions
unknown
Extent
V, 223 p. 24 illus., 23 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789402411706
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-94-024-1170-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-94-024-1170-6

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