The Resource Immunopathology in Toxicology and Drug Development : Volume 1, Immunobiology, Investigative Techniques, and Special Studies, edited by George A. Parker, (electronic resource)

Immunopathology in Toxicology and Drug Development : Volume 1, Immunobiology, Investigative Techniques, and Special Studies, edited by George A. Parker, (electronic resource)

Label
Immunopathology in Toxicology and Drug Development : Volume 1, Immunobiology, Investigative Techniques, and Special Studies
Title
Immunopathology in Toxicology and Drug Development
Title remainder
Volume 1, Immunobiology, Investigative Techniques, and Special Studies
Statement of responsibility
edited by George A. Parker
Contributor
Editor
Provider
Subject
Language
eng
Summary
This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Member of
Image bit depth
0
LC call number
RB1-214
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Parker, George A.
  • SpringerLink
Series statement
Molecular and Integrative Toxicology,
http://library.link/vocab/subjectName
  • Medicine
  • Immunology
  • Pharmaceutical technology
  • Clinical biochemistry
  • Pathology
  • Medicine & Public Health
  • Pathology
  • Immunology
  • Pharmaceutical Sciences/Technology
  • Medical Biochemistry
Label
Immunopathology in Toxicology and Drug Development : Volume 1, Immunobiology, Investigative Techniques, and Special Studies, edited by George A. Parker, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Basic Immunobiology -- Cells of the Immune System -- Signaling and effector molecules in immunity -- Development of immune system organs -- Aging of immune system organs -- Flow cytometry and immunophenotyping in drug development -- Pathology evaluation for detection of immunomodulation -- Enhanced immunohistopathology -- Clinical Pathology Assays in Immunopathology -- Application of immunohistochemistry in toxicologic pathology of the hematolymphoid system -- Morphometry and stereology in immunopathology -- Molecular techniques in immunopathology -- Current issues in developmental immunotoxicity -- The Murine local lymph node assay -- Host Resistance assays for efficacy and immunotoxicology safety evaluations.
Dimensions
unknown
Extent
XXII, 670 p. 255 illus., 250 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319473772
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-47377-2
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-47377-2
Label
Immunopathology in Toxicology and Drug Development : Volume 1, Immunobiology, Investigative Techniques, and Special Studies, edited by George A. Parker, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Basic Immunobiology -- Cells of the Immune System -- Signaling and effector molecules in immunity -- Development of immune system organs -- Aging of immune system organs -- Flow cytometry and immunophenotyping in drug development -- Pathology evaluation for detection of immunomodulation -- Enhanced immunohistopathology -- Clinical Pathology Assays in Immunopathology -- Application of immunohistochemistry in toxicologic pathology of the hematolymphoid system -- Morphometry and stereology in immunopathology -- Molecular techniques in immunopathology -- Current issues in developmental immunotoxicity -- The Murine local lymph node assay -- Host Resistance assays for efficacy and immunotoxicology safety evaluations.
Dimensions
unknown
Extent
XXII, 670 p. 255 illus., 250 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319473772
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-47377-2
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-47377-2

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