Coverart for item
The Resource Induced pluripotent stem cells in brain diseases : understanding the methods, epigenetic basis, and applications for regenerative medicine, Vivi M. Heine ... [et al.], (electronic resource)

Induced pluripotent stem cells in brain diseases : understanding the methods, epigenetic basis, and applications for regenerative medicine, Vivi M. Heine ... [et al.], (electronic resource)

Label
Induced pluripotent stem cells in brain diseases : understanding the methods, epigenetic basis, and applications for regenerative medicine
Title
Induced pluripotent stem cells in brain diseases
Title remainder
understanding the methods, epigenetic basis, and applications for regenerative medicine
Statement of responsibility
Vivi M. Heine ... [et al.]
Contributor
Provider
Subject
Language
eng
Summary
The principle goal of regenerative medicine is the restoration of damaged, dysfunctional, or missing cellular tissue, up to and including whole organs. Growing healthy replacement tissue, in vivo or in vitro, plays an important role in anticipated therapies. To generate competent replacement material, scientists confront the fundamental issues of cellular identity and plasticity. The basis of this book is formed by the theses of three talented master students: Stephanie Dooves, Dwayne Holmes and Judith Wagner. Their work discusses the recent advancements in the field of cell reprogramming. Although it is clear that we can produce pluripotent stem cells from differentiated cells, there are still a lot of unsolved issues. These issues include the efficiency and safety of reprogramming, the similarity of induced pluripotent (iPSCs) to embryonic stem cells (ESCs) and the epigenetic status of the cells. In the third chapter, the use of stem cell therapy for brain diseases will be discussed, with a focus on Parkinson’s disease (PD) and Vanishing White Matter (VWM)
Member of
Cataloging source
GW5XE
Image bit depth
0
LC call number
QH588.S83
LC item number
I53 2012
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • SpringerLink
  • Heine, Vivi M
Series statement
SpringerBriefs in Neuroscience,
http://library.link/vocab/subjectName
  • Regenerative medicine
  • Stem cells
  • Nervous system
  • Nervous system
  • Regenerative medicine
  • Stem cells
Label
Induced pluripotent stem cells in brain diseases : understanding the methods, epigenetic basis, and applications for regenerative medicine, Vivi M. Heine ... [et al.], (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references
Color
not applicable
Contents
I. Introduction.- II. Cell Reprogramming: A New Era in Regenerative Medicine -- a. Stem Cells -- b. Reprogramming Methods.- c. Measuring Pluripotency, Efficiency, and Identity -- d. Induced Pluripotent Stem Cells versus Embryonic Stem Cells -- III. Understanding Epigenetic Memory is the Key to Successful Reprogramming -- a. Pre-fertilization to Embryo -- b. Epigenetic Control in De-, Re-, and Trans-differentiation -- IV. Prospects for Cell Replacement Therapies for Brain Diseases -- a. Parkinson’s Disease -- b. Childhood Brain White Matter Disorders -- V. Conclusions.- VI. Acknowledgement -- VII. References
Dimensions
unknown
Extent
1 online resource (xv, 59 p.)
File format
multiple file formats
Form of item
  • online
  • electronic
Isbn
9789400728165
Level of compression
uncompressed
Other physical details
ill. (some col.)
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (OCoLC)765949030
  • (OCoLC)ocn765949030
Label
Induced pluripotent stem cells in brain diseases : understanding the methods, epigenetic basis, and applications for regenerative medicine, Vivi M. Heine ... [et al.], (electronic resource)
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references
Color
not applicable
Contents
I. Introduction.- II. Cell Reprogramming: A New Era in Regenerative Medicine -- a. Stem Cells -- b. Reprogramming Methods.- c. Measuring Pluripotency, Efficiency, and Identity -- d. Induced Pluripotent Stem Cells versus Embryonic Stem Cells -- III. Understanding Epigenetic Memory is the Key to Successful Reprogramming -- a. Pre-fertilization to Embryo -- b. Epigenetic Control in De-, Re-, and Trans-differentiation -- IV. Prospects for Cell Replacement Therapies for Brain Diseases -- a. Parkinson’s Disease -- b. Childhood Brain White Matter Disorders -- V. Conclusions.- VI. Acknowledgement -- VII. References
Dimensions
unknown
Extent
1 online resource (xv, 59 p.)
File format
multiple file formats
Form of item
  • online
  • electronic
Isbn
9789400728165
Level of compression
uncompressed
Other physical details
ill. (some col.)
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (OCoLC)765949030
  • (OCoLC)ocn765949030

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