The Resource Lifestyle interventions for four conditions : type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer, University of Alberta Evidence-based Practice Center ; Elizabeth Sumamo, Christine Ha, Christina Korownyk, Ben Vandermeer, Donna M. Dryden

Lifestyle interventions for four conditions : type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer, University of Alberta Evidence-based Practice Center ; Elizabeth Sumamo, Christine Ha, Christina Korownyk, Ben Vandermeer, Donna M. Dryden

Label
Lifestyle interventions for four conditions : type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer
Title
Lifestyle interventions for four conditions
Title remainder
type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer
Statement of responsibility
University of Alberta Evidence-based Practice Center ; Elizabeth Sumamo, Christine Ha, Christina Korownyk, Ben Vandermeer, Donna M. Dryden
Creator
Contributor
Author
Issuing body
Subject
Language
  • eng
  • eng
Summary
OBJECTIVES: To synthesize evidence from randomized controlled trials (RCTs) on the effectiveness of lifestyle interventions to control progression of type 2 diabetes, progression to diabetes from metabolic syndrome, or recurrence of breast cancer and prostate cancer. Lifestyle interventions were defined as any intervention that included exercise, diet, and at least one other component (e.g., counseling, stress management, smoking cessation). DATA SOURCES: A systematic and comprehensive literature search was conducted to identify RCTs from 1980 to the present. REVIEW METHODS: Study selection, quality assessment, and data extraction were completed by several investigators in duplicate and independently. Random effects models were used for meta-analyses. RESULTS: From 1,288 citations, we included 20 unique RCTs (plus 80 associated publications): diabetes = 10 studies, metabolic syndrome = 7, breast and prostate cancer = 3. All studies had a "high" or "unclear" risk of bias. Type 2 diabetes: One RCT reported that, at 13 years postintervention, the lifestyle intervention group had fewer nonfatal strokes, reduced incidence of retinopathy, reduced progression of autonomic neuropathy, and reduced incidence of nephropathy. In this trial the lifestyle intervention included pharmacotherapy. A number of studies reported positive effects for lifestyle interventions on changes in body composition, metabolic variables, physical activity, and dietary intake; however, the results were not always statistically significant and were not always sustained following the end of the active intervention. Metabolic syndrome: Four studies reported that lifestyle interventions decreased the risk of developing type 2 diabetes. Most studies also reported positive effects for changes in body composition, metabolic variables, physical activity, and dietary intake. The results were not always statistically significant and were not always sustained following the end of the active intervention. Breast and prostate cancer: One RCT on prostate cancer reported that the lifestyle intervention decreased PSA levels. Two studies reported positive effects for changes in body composition, metabolic variables, physical activity, and dietary intake; however, the results generally were not statistically significant. CONCLUSIONS: Comprehensive lifestyle interventions that include exercise, dietary changes, and at least one other component are effective in decreasing the incidence of type 2 diabetes mellitus in high risk patients and the benefit extends beyond the active intervention phase. In patients who have already been diagnosed with type 2 diabetes, there is some evidence to suggest long-term benefit on microvascular and macrovascular outcomes, although the evidence is from one trial of high risk diabetic patients and included pharmacotherapy. The evidence for lifestyle interventions to prevent cancer recurrence is insufficient to draw conclusions. Comprehensive lifestyle interventionsappear to have a positive impact on behavioral outcomes including exercise and dietary intake, as well as a number of metabolic variables, at least in the short-term in all populations addressed in this report
Member of
http://library.link/vocab/creatorName
Sumamo Schellenberg, Elizabeth
Government publication
federal national government publication
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • surveys of literature
  • statistics
http://library.link/vocab/relatedWorkOrContributorName
  • Ha, Christine
  • Korownyk, Christina
  • Vandermeer, Ben
  • Dryden, Donna M.
  • University of Alberta Evidence-based Practice Center
  • United States
  • Technology Assessment Program (Agency for Healthcare Research and Quality)
Series statement
  • Technology assessment
  • NCBI Bookshelf
http://library.link/vocab/subjectName
  • Health Behavior
  • Life Style
  • Diabetes Mellitus, Type 2
  • Metabolic Syndrome X
  • Breast Neoplasms
  • Prostatic Neoplasms
  • Randomized Controlled Trials as Topic
Label
Lifestyle interventions for four conditions : type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer, University of Alberta Evidence-based Practice Center ; Elizabeth Sumamo, Christine Ha, Christina Korownyk, Ben Vandermeer, Donna M. Dryden
Instantiates
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (1 PDF file (various pagings))
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
System control number
(EXLCZ)993710000000379831
Label
Lifestyle interventions for four conditions : type 2 diabetes, metabolic syndrome, breast cancer, and prostate cancer, University of Alberta Evidence-based Practice Center ; Elizabeth Sumamo, Christine Ha, Christina Korownyk, Ben Vandermeer, Donna M. Dryden
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (1 PDF file (various pagings))
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
System control number
(EXLCZ)993710000000379831

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