The Resource Mass spectrometry for drug discovery and drug development, edited by Walter A. Korfmacher, (electronic resource)

Mass spectrometry for drug discovery and drug development, edited by Walter A. Korfmacher, (electronic resource)

Label
Mass spectrometry for drug discovery and drug development
Title
Mass spectrometry for drug discovery and drug development
Statement of responsibility
edited by Walter A. Korfmacher
Contributor
Provider
Subject
Language
eng
Summary
This book presents a summary of the ways mass spectrometry is used in various stages of drug discovery and development including early support of medicinal chemistry, drug metabolism studies, distribution, degradation, and various development assays. The book includes a balance of basic and advanced information. Specific chapters relate to various stages in the process (e.g., discovery) as well as chapters on topics of current interest (lipidomics and SiRNA) are covered
Member of
Cataloging source
MHW
Illustrations
  • illustrations
  • plates
Index
index present
LC call number
RS189.5.S65
LC item number
M37 2013eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QV 745
http://library.link/vocab/relatedWorkOrContributorName
  • ebrary
  • Korfmacher, Walter A
Series statement
Wiley series on mass spectrometry
http://library.link/vocab/subjectName
  • Drugs
  • Drug development
  • Mass spectrometry
  • Drug Discovery
  • Mass Spectrometry
  • Peptides
  • Pharmaceutical Preparations
  • Proteins
  • Drug discovery
  • Mass spectrometry
  • Peptides
  • Pharmaceutical preparations
  • Proteins
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Drug development
  • Drugs
  • Mass spectrometry
Label
Mass spectrometry for drug discovery and drug development, edited by Walter A. Korfmacher, (electronic resource)
Instantiates
Publication
Note
Description based on print version record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gérard Hopfgartner -- 2. Utility of high-resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendra N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark T. Cancilla and W. Michael Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high-resolution full scan? / Lieve Dillen and Filip Cuyckens
Dimensions
unknown
Extent
1 online resource (xii, 461 pages, [16] pages of plates))
Form of item
online
Isbn
9781283917520
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Reproduction note
Electronic reproduction.
Specific material designation
remote
Stock number
10.1002/9781118516157
System control number
  • (OCoLC)823389939
  • (OCoLC)ocn823389939
Label
Mass spectrometry for drug discovery and drug development, edited by Walter A. Korfmacher, (electronic resource)
Publication
Note
Description based on print version record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gérard Hopfgartner -- 2. Utility of high-resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendra N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark T. Cancilla and W. Michael Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high-resolution full scan? / Lieve Dillen and Filip Cuyckens
Dimensions
unknown
Extent
1 online resource (xii, 461 pages, [16] pages of plates))
Form of item
online
Isbn
9781283917520
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Reproduction note
Electronic reproduction.
Specific material designation
remote
Stock number
10.1002/9781118516157
System control number
  • (OCoLC)823389939
  • (OCoLC)ocn823389939

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