The Resource Mechanisms of stimulus-response coupling in platelets, edited by J. Westwick [and others]

Mechanisms of stimulus-response coupling in platelets, edited by J. Westwick [and others]

Label
Mechanisms of stimulus-response coupling in platelets
Title
Mechanisms of stimulus-response coupling in platelets
Statement of responsibility
edited by J. Westwick [and others]
Contributor
Subject
Genre
Language
eng
Summary
Since its inception the research area of platelet pharmacology has always been a vigorous one and it is a characteristic that new approaches to the understanding of platelet function are rapidly and thoroughly investigated. The intensity of this activity is attributable, probably, to an appreciation by research workers in the field that a satisfactory therapeutic control of platelet function trolling platelet function is achieved the benefits to clinical medicine will be immense since platelets are known to be involved in a multiplicity of events coupled within the haemostatic mechanisms and inflammatory responses. Aberrations in the behavior of platelets is part of the aetiology of atherosclerosis, myocardial and cerebral infarction and thrombosis. At this point in time, research in platelet function is in a particularly rapid state of flux. The recent findings of research workers active in the field and also workers investigating mechanisms of stimulus response coupling in other cells, have provided interesting insights into the generality of mechanisms involved in the function insights into the generality of mechanisms involved in the function of responsive cells. One may itemize these developments as the area cell receptor/ligand interaction, induction of cellular response by protein phosphorylation and calcium flux. The mechanism of these latter events occurs through the activity of phospholipase generating transient intermediates. These intermediates may act as ionophores or enzyme activators or may, in the case of eicosanoids, reinforce and make irreversible the cellular response. Other developments related to platelet function have been in understanding of the functionalities of platelets in their interactions with other cellular and vascular elements, and components of the coagulation system. Because of the rapid developments which were occurring the symposium MECHANIAMS OF STIMULUS RESPONSE COUPLING IN PLATELETS was organized and took place at the Institute of Psychiatry, University of London, on 26th and 27th September 1984, and was attended by 300 participants. The format of this book is the same as that of the symposium and was designed to examine in sequence each of the steps in platelet functionality from primary interaction between ligand and receptor through to the functional interaction with other physiological elements
Member of
Cataloging source
DNLM/DLC
Index
no index present
LC call number
QP97
LC item number
.M39 1985
Literary form
non fiction
NAL call number
QP901.A33
NAL item number
v.192
Nature of contents
bibliography
NLM call number
  • W1
  • WH 310
NLM item number
  • AD559 v.192 1985
  • M4865 1984
http://library.link/vocab/relatedWorkOrContributorName
Westwick, J
Series statement
Advances in experimental medicine and biology
Series volume
v. 192
http://library.link/vocab/subjectName
  • Blood platelets
  • Cell receptors
  • Blood Platelets
  • Platelet Aggregation
  • Sang
  • Récepteurs cellulaires
  • Blood platelets
  • Cell receptors
Label
Mechanisms of stimulus-response coupling in platelets, edited by J. Westwick [and others]
Instantiates
Publication
Note
"Proceedings of a symposium ... held September 27-28, 1984, in De Crespigny Park, London, England"--T.p. verso
Bibliography note
Includes bibliographies and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
26 cm.
Extent
xi, 444 pages
Isbn
9780306420733
Lccn
85012135
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
  • (OCoLC)12162828
  • (OCoLC)ocm12162828
Label
Mechanisms of stimulus-response coupling in platelets, edited by J. Westwick [and others]
Publication
Note
"Proceedings of a symposium ... held September 27-28, 1984, in De Crespigny Park, London, England"--T.p. verso
Bibliography note
Includes bibliographies and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
26 cm.
Extent
xi, 444 pages
Isbn
9780306420733
Lccn
85012135
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
  • (OCoLC)12162828
  • (OCoLC)ocm12162828

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