The Resource Network medicine : complex systems in human disease and therapeutics, edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman

Network medicine : complex systems in human disease and therapeutics, edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman

Label
Network medicine : complex systems in human disease and therapeutics
Title
Network medicine
Title remainder
complex systems in human disease and therapeutics
Statement of responsibility
edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman
Contributor
Editor
Subject
Language
eng
Summary
"Network medicine, a new field which developed from the application of systems biology approaches to human disease, embraces the complexity of multifactorial influences on disease, which can be driven by non-linear effects and molecular and statistical interactions. The development of comprehensive and affordable Omics platforms provides the data types for network medicine, and graph theory and statistical physics provide the theoretical framework to analyze networks. While network medicine provides a fundamentally different approach to understanding disease etiology, it will also lead to key differences in how diseases are treated--with multiple molecular targets that may require manipulation in a coordinated, dynamic fashion. Much remains to be learned regarding the optimal approaches to integrate different Omics data types and to perform network analyses; this book provides an overview of the progress that has been made and the challenges that remain."--
Assigning source
Provided by publisher
Cataloging source
MH/DLC
Illustrations
illustrations
Index
index present
LC call number
R858
LC item number
.N48 2017
Literary form
non fiction
NLM call number
QU 26.5 L879n 2017
http://library.link/vocab/relatedWorkOrContributorName
  • Loscalzo, Joseph
  • Barabási, Albert-László
  • Silverman, Edwin K.
http://library.link/vocab/subjectName
  • Medizinische Informatik
  • Medical informatics
  • Data integration (Computer science)
  • Diseases
  • Therapeutics
  • Systems Biology
  • Molecular Biology
  • Gene Regulatory Networks
  • Medical Informatics Computing
  • Disease
  • Data integration (Computer science)
  • Medical informatics
  • Therapeutics
Label
Network medicine : complex systems in human disease and therapeutics, edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman
Instantiates
Publication
Note
Includes index
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Scientific basis of network medicine / Edwin K. Silverman and Joseph Loscalzo -- Introduction to network analysis / Jorg Menche and Albert-Laszlo Barabasi -- Human interactomes in network medicine / Michael E. Cusick, Benoit Charloteaux, Thomas Rolland, Michael A. Calderwood, David E. Hill, and Marc Vidal -- Social networks in human disease / Martin W. Schoen and Douglas Luke -- Phenotype, pathophenotype and endo(patho)phenotype in network medicine / Calum A. MacRae -- A new paradigm for defining human disease and therapy / Joseph Loscalzo -- Complex disease genetics and network medicine / Edwin K. Silverman -- Transcriptomics and network medicine / Kimberly Glass and John Quackenbush -- Post-translational modifications of the proteome: the example of Tau in the neuron and the brain / Guy Lippens, Jeremy Gunawardena, Isabelle Landrieu, Caroline Smet-Nocca, Sudhakaran Prabakaran, Benjamin Parent, Arnaud Leroy, and I. Huvent -- Epigenetics and network medicine / Dawn L. DeMeo and Scott T. Weiss -- Metabolomics and network medicine / Jessica Lasky-Su and Clary B. Clish -- Using integrative Omics approaches in network medicine / Shuyi Ma, John C. Earls, James A. Eddy, and Nathan D. Price -- Cancer network medicine / Takeshi Hase, Samik Ghosh, Sucheendra K Palaniappan, and Hiroaki Kitano -- Systems pharmacology in network medicine / Edwin K. Silverman and Joseph Loscalzo -- Systems approaches to clinical trials / Elliott M. Antman -- Microbiomics in network medicine / Joanne E. Sordillo, George M. Weinstock, and Augusto A. Litonjua
Dimensions
25 cm
Extent
xi, 436 pages
Isbn
9780674436534
Lccn
2016006644
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations (chiefly color)
System control number
  • (OCoLC)939597214
  • (OCoLC)ocn939597214
Label
Network medicine : complex systems in human disease and therapeutics, edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman
Publication
Note
Includes index
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Scientific basis of network medicine / Edwin K. Silverman and Joseph Loscalzo -- Introduction to network analysis / Jorg Menche and Albert-Laszlo Barabasi -- Human interactomes in network medicine / Michael E. Cusick, Benoit Charloteaux, Thomas Rolland, Michael A. Calderwood, David E. Hill, and Marc Vidal -- Social networks in human disease / Martin W. Schoen and Douglas Luke -- Phenotype, pathophenotype and endo(patho)phenotype in network medicine / Calum A. MacRae -- A new paradigm for defining human disease and therapy / Joseph Loscalzo -- Complex disease genetics and network medicine / Edwin K. Silverman -- Transcriptomics and network medicine / Kimberly Glass and John Quackenbush -- Post-translational modifications of the proteome: the example of Tau in the neuron and the brain / Guy Lippens, Jeremy Gunawardena, Isabelle Landrieu, Caroline Smet-Nocca, Sudhakaran Prabakaran, Benjamin Parent, Arnaud Leroy, and I. Huvent -- Epigenetics and network medicine / Dawn L. DeMeo and Scott T. Weiss -- Metabolomics and network medicine / Jessica Lasky-Su and Clary B. Clish -- Using integrative Omics approaches in network medicine / Shuyi Ma, John C. Earls, James A. Eddy, and Nathan D. Price -- Cancer network medicine / Takeshi Hase, Samik Ghosh, Sucheendra K Palaniappan, and Hiroaki Kitano -- Systems pharmacology in network medicine / Edwin K. Silverman and Joseph Loscalzo -- Systems approaches to clinical trials / Elliott M. Antman -- Microbiomics in network medicine / Joanne E. Sordillo, George M. Weinstock, and Augusto A. Litonjua
Dimensions
25 cm
Extent
xi, 436 pages
Isbn
9780674436534
Lccn
2016006644
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations (chiefly color)
System control number
  • (OCoLC)939597214
  • (OCoLC)ocn939597214

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