The Resource Newer drugs for insomnia : final report update 2, Susan Carson ... [et al.], (electronic resource)

Newer drugs for insomnia : final report update 2, Susan Carson ... [et al.], (electronic resource)

Label
Newer drugs for insomnia : final report update 2
Title
Newer drugs for insomnia
Title remainder
final report update 2
Statement of responsibility
Susan Carson ... [et al.]
Title variation
Drug class review : newer drugs for insomnia
Creator
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
Insomnia is a serious health problem that affects millions of people. Population surveys have estimated the prevalence of insomnia to be about 30% to 50% of the general population. About three-fourths of people who have trouble sleeping say that the problem is "occasional," averaging about 6 nights per month, with one-fourth having frequent or chronic insomnia, averaging about 16 nights per month. Individuals with insomnia most often report a combination of difficulty falling asleep and intermittent wakefulness during sleep. Treatment of insomnia involves behavioral changes, such as minimizing habits that interfere with sleep (for example, drinking coffee or engaging in stressful activities in the evening), and pharmacotherapy with sedating antidepressants (for example, trazodone), sedating antihistamines, anticholinergics, benzodiazepines, or nonbenzodiazepine hypnotics. The benzodiazepines and the newer sedative hypnotics zolpidem, zaleplon, zopiclone, and eszopiclone work through gamma-aminobutyric acid receptors. Ramelteon, a hypnotic approved by the United States Food and Drug Administration (FDA) in July 2005, is a selective melatonin receptor (MT1 and MT2) agonist. New nonbenzodiazepine drugs have been sought for multiple reasons, including reduction of the risk of tolerance, dependence, and abuse associated with benzodiazepines. The purpose of this review is to evaluate the comparative evidence on benefits and harms of these medications in people with insomnia to help policymakers and clinicians make informed choices about the use of newer drugs for insomnia
Member of
Cataloging source
DNLM
http://library.link/vocab/creatorName
Carson, Susan
Funding information
The funding source, the Center for Evidence-based Policy, is supported by 17 organizations, including 15 state Medicaid programs. These organizations selected the topic and had input into the Key Questions of this review. The content and conclusions of the review are entirely determined by the Evidence-based Practice Center researchers. The authors of this report have no financial interest in any company that makes or distributes the products reviewed in this report.
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • surveys of literature
NLM call number
WL 108
http://library.link/vocab/relatedWorkOrContributorName
  • Drug Effectiveness Review Project
  • Oregon Health & Science University
  • Oregon Health & Science University
Series statement
Drug class review
http://library.link/vocab/subjectName
  • Sleep Initiation and Maintenance Disorders
  • Drug Evaluation
  • Clinical Trials as Topic
Label
Newer drugs for insomnia : final report update 2, Susan Carson ... [et al.], (electronic resource)
Instantiates
Publication
Note
  • "October 2008."
  • Title from PDF cover (viewed May 17, 2011)
Bibliography note
Includes bibliographical references
Color
black and white
Dimensions
unknown
Extent
1 online resource (1 PDF file (309 p.))
Form of item
online
Specific material designation
remote
System control number
  • 1553947
  • (DNLM)BKSHLF:NBK47207
Label
Newer drugs for insomnia : final report update 2, Susan Carson ... [et al.], (electronic resource)
Publication
Note
  • "October 2008."
  • Title from PDF cover (viewed May 17, 2011)
Bibliography note
Includes bibliographical references
Color
black and white
Dimensions
unknown
Extent
1 online resource (1 PDF file (309 p.))
Form of item
online
Specific material designation
remote
System control number
  • 1553947
  • (DNLM)BKSHLF:NBK47207

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