The Resource Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application, by Youngjun Lee, (electronic resource)

Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application, by Youngjun Lee, (electronic resource)

Label
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application
Title
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
Title remainder
Synthesis, Analysis and Application
Statement of responsibility
by Youngjun Lee
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials
Member of
http://library.link/vocab/creatorName
Lee, Youngjun
Image bit depth
0
LC call number
TP248.3
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
SpringerLink
Series statement
Springer Theses, Recognizing Outstanding Ph.D. Research,
http://library.link/vocab/subjectName
  • Chemistry
  • Microbiology
  • Biochemical engineering
  • Bioorganic chemistry
  • Biomedical engineering
  • Chemistry
  • Biochemical Engineering
  • Bioorganic Chemistry
  • Biological and Medical Physics, Biophysics
  • Biomedical Engineering
  • Applied Microbiology
Label
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application, by Youngjun Lee, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Abstract -- Table of Contents -- List of Figures -- List of Tables -- List of Schemes -- List of Abbreviations -- Chapter 1. Introduction -- 1.1 Molecular Fluorescence and Photophysical Parameters -- 1.2 Organic Fluorophores -- 1.3 Aims and Scope of the Thesis -- 1.4 References -- Chapter 2. A Comprehensive Studies of an Indolizine-Based Seoul-Fluor System -- 2.1 Structure and Quantum Yield Relationship Study of Seoul-Fluor -- 2.2 Optimization of SF-Based Lipid Droplet Bioprobes on the basis of Molecular Lipophilicity -- 2.3 An Overview of Seoul-Fluor System -- 2.4 References -- 2.5 Experimental Section -- Chapter 3. Tetrazine-Containing Colorful Bioorthogonal Probes based on the Indolizine Core Skeleton -- 3.1 Introduction. -3.2 Result and Discussion -- 3.3 Conclusion -- 3.4 References -- 3.5 Experimental Section -- Chapter 4. Rational Development of Furoindolizine Core Skeleton Guided by Oscillator Strength -- 4.1 Introduction -- 4.2 Result and Discussion -- 4.3 Conclusion -- 4.4 References -- 4.5 Experimental Section.
Dimensions
unknown
Extent
XXV, 187 p. 197 illus., 90 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789811316456
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-981-13-1645-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-981-13-1645-6
Label
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application, by Youngjun Lee, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Abstract -- Table of Contents -- List of Figures -- List of Tables -- List of Schemes -- List of Abbreviations -- Chapter 1. Introduction -- 1.1 Molecular Fluorescence and Photophysical Parameters -- 1.2 Organic Fluorophores -- 1.3 Aims and Scope of the Thesis -- 1.4 References -- Chapter 2. A Comprehensive Studies of an Indolizine-Based Seoul-Fluor System -- 2.1 Structure and Quantum Yield Relationship Study of Seoul-Fluor -- 2.2 Optimization of SF-Based Lipid Droplet Bioprobes on the basis of Molecular Lipophilicity -- 2.3 An Overview of Seoul-Fluor System -- 2.4 References -- 2.5 Experimental Section -- Chapter 3. Tetrazine-Containing Colorful Bioorthogonal Probes based on the Indolizine Core Skeleton -- 3.1 Introduction. -3.2 Result and Discussion -- 3.3 Conclusion -- 3.4 References -- 3.5 Experimental Section -- Chapter 4. Rational Development of Furoindolizine Core Skeleton Guided by Oscillator Strength -- 4.1 Introduction -- 4.2 Result and Discussion -- 4.3 Conclusion -- 4.4 References -- 4.5 Experimental Section.
Dimensions
unknown
Extent
XXV, 187 p. 197 illus., 90 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789811316456
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-981-13-1645-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-981-13-1645-6

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