The Resource Targeted immune modulators : final report update 2, Gerald Gartlehner ... [et al.] ; produced by RTI-UNC Evidence-based Practice Center, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill ... [et al.], (electronic resource)

Targeted immune modulators : final report update 2, Gerald Gartlehner ... [et al.] ; produced by RTI-UNC Evidence-based Practice Center, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill ... [et al.], (electronic resource)

Label
Targeted immune modulators : final report update 2
Title
Targeted immune modulators
Title remainder
final report update 2
Statement of responsibility
Gerald Gartlehner ... [et al.] ; produced by RTI-UNC Evidence-based Practice Center, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill ... [et al.]
Title variation
Drug class review : targeted immune modulators
Creator
Contributor
Subject
Language
  • eng
  • eng
Summary
Targeted immune modulators, commonly referred to as biological response modifiers or simply biologics, are a relatively new category of medications used in the treatment of certain types of immunologic and inflammatory diseases, including rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. The US Food and Drug Administration approved the first of the biologics (infliximab) in 1998 and approved 9 additional agents since that time for treating various rheumatic conditions and plaque psoriasis: etanercept (1998), anakinra (2001), adalimumab (2002), alefacept (2003), efalizumab (2003), abatacept (2005), rituximab (2006), natalizumab (2008), and certolizumab pegol (2008). In this report, we review the comparative effectiveness, safety, and tolerability of targeted immune modulators
Member of
Cataloging source
DNLM
http://library.link/vocab/creatorName
Gartlehner, Gerald
Funding information
The Drug Effectiveness Review Project, composed of 15 organizations including 14 state Medicaid agencies, and the Canadian Agency for Drugs and Technology in Health commissioned and funded for this report. These organizations selected the topic of the report and had input into its Key Questions. The content and conclusions of the report were entirely determined by the Evidence-based Practice Center researchers. The authors of this report have no financial interest in any company that makes or distributes the products reviewed in this report.
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • surveys of literature
NLM call number
QW 575
http://library.link/vocab/relatedWorkOrContributorName
  • Gartlehner, Gerald
  • Drug Effectiveness Review Project
  • Research Triangle Institute-University of North Carolina at Chapel Hill Evidence-based Practice Center
  • Oregon Health & Science University
  • Oregon Health & Science University
Series statement
Drug class review
http://library.link/vocab/subjectName
  • Immunoconjugates
  • Immunologic Factors
  • Arthritis
  • Inflammatory Bowel Diseases
  • Clinical Trials as Topic
Label
Targeted immune modulators : final report update 2, Gerald Gartlehner ... [et al.] ; produced by RTI-UNC Evidence-based Practice Center, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill ... [et al.], (electronic resource)
Instantiates
Publication
Note
  • "November 2009."
  • Title from PDF cover (viewed May 17, 2011)
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource (1 PDF file (637 p.))
Form of item
online
Specific material designation
remote
System control number
  • 1553951
  • (DNLM)BKSHLF:NBK47225
Label
Targeted immune modulators : final report update 2, Gerald Gartlehner ... [et al.] ; produced by RTI-UNC Evidence-based Practice Center, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill ... [et al.], (electronic resource)
Publication
Note
  • "November 2009."
  • Title from PDF cover (viewed May 17, 2011)
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource (1 PDF file (637 p.))
Form of item
online
Specific material designation
remote
System control number
  • 1553951
  • (DNLM)BKSHLF:NBK47225

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