The Resource The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey, by P. Colm Malone, Paul S. Agutter, (electronic resource)

The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey, by P. Colm Malone, Paul S. Agutter, (electronic resource)

Label
The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey
Title
The Aetiology of Deep Venous Thrombosis
Title remainder
A Critical, Historical and Epistemological Survey
Statement of responsibility
by P. Colm Malone, Paul S. Agutter
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
What we now call ‘deep venous thrombosis’ (DVT) has been elucidated by a diversity of investigative approaches during the past four centuries. The authors of this book survey the history of the field and ask: why has one of these perspectives – the haematological/biochemical – come to dominate research into the causation of DVT during the past 50 years and to exclude alternatives? In answering this question, they show that the current consensus model is conceptually flawed. Building on the work of William Harvey, John Hunter, Rudolf Virchow, Ludwig Aschoff and a number of pathologists in the mid-20th century, they offer a revised account of the aetiology of this condition. In the process they retrace and review the 160-year-old philosophical and methodological schism in biomedical research and, using DVT as an example, propose how this schism might be bridged to the benefit of both research and clinical practice
Member of
http://library.link/vocab/creatorName
Malone, P. Colm
Image bit depth
0
LC call number
RB45
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Agutter, Paul S.
  • SpringerLink
http://library.link/vocab/subjectName
  • Medicine
  • medicine
  • Hematology
  • Pathology
  • Vascular Surgery
  • Medicine & Public Health
  • Hematology
  • Pathology
  • History of Medicine
  • Vascular Surgery
  • Philosophy of Medicine
Label
The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey, by P. Colm Malone, Paul S. Agutter, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
to the Study of Deep Venous Thrombosis -- The Coagulation Cascade and the Consensus Model of DVT -- Hypercoagulability -- Historical Roots -- Coagulation and its Disorders: A History of Haematological Research -- Virchow and the Pathophysiological Tradition in the 19th Century -- The Pathophysiological Tradition after Virchow -- Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves -- Underperfusion of Valve Pockets and the Initiation of DVT -- The Role of Endothelial Hypoxia in DVT -- The Valve Cusp Hypoxia Hypothesis -- Molecular Changes in the Hypoxic Endothelium -- Cadaver Clots or Agonal Thrombi?
Dimensions
unknown
File format
multiple file formats
Form of item
electronic
Isbn
9781402066504
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4020-6650-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-4020-6650-4
Label
The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey, by P. Colm Malone, Paul S. Agutter, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
to the Study of Deep Venous Thrombosis -- The Coagulation Cascade and the Consensus Model of DVT -- Hypercoagulability -- Historical Roots -- Coagulation and its Disorders: A History of Haematological Research -- Virchow and the Pathophysiological Tradition in the 19th Century -- The Pathophysiological Tradition after Virchow -- Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves -- Underperfusion of Valve Pockets and the Initiation of DVT -- The Role of Endothelial Hypoxia in DVT -- The Valve Cusp Hypoxia Hypothesis -- Molecular Changes in the Hypoxic Endothelium -- Cadaver Clots or Agonal Thrombi?
Dimensions
unknown
File format
multiple file formats
Form of item
electronic
Isbn
9781402066504
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4020-6650-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-4020-6650-4

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