The Resource The BRICHOS Domain : Its Proproteins and Functions, by Jenny Presto, Jan Johansson, (electronic resource)

The BRICHOS Domain : Its Proproteins and Functions, by Jenny Presto, Jan Johansson, (electronic resource)

Label
The BRICHOS Domain : Its Proproteins and Functions
Title
The BRICHOS Domain
Title remainder
Its Proproteins and Functions
Statement of responsibility
by Jenny Presto, Jan Johansson
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
This Brief summarizes the current research on the novel BRICHOS domain, which is a chaperone domain found in a variety of proteins and is shown to exhibit anti-amyloidogenic chaperone-like functions. The BRICHOS domain is defined from sequence similarities, lacks established physiological function(s) and is found about 10 distantly related pro-protein families, several of which are associated with human disease. In this work, the authors review the mechanism by which BRICHOS inhibits Aβ aggregation and examine recent results from in vivo experiments where BRICHOS inhibits Aβ aggregation and toxicity in Drosophila melanogaster. BRICHOS is one of nature ́s (more specific) ways to protect against fibril formation, and exploring the potential of using the BRICHOS domain in the fight against Alzeimer's Disease and other amyloid diseases seems highly relevant. This brief is useful for newcomers to this field or researchers in related fields wishing to gain a quick overview of the latest findings
Member of
http://library.link/vocab/creatorName
Presto, Jenny
Image bit depth
0
LC call number
QD241-441
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Johansson, Jan.
  • SpringerLink
Series statement
SpringerBriefs in Molecular Science,
http://library.link/vocab/subjectName
  • Chemistry
  • Bioorganic chemistry
  • Biochemistry
  • Chemistry
  • Bioorganic Chemistry
  • Protein Structure
Label
The BRICHOS Domain : Its Proproteins and Functions, by Jenny Presto, Jan Johansson, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction to BRICHOS Superfamily -- BRICHOS in proSP-C -- Proteins with a BRICHOS Domain -- Aβ Amyloid Formation in Alzheimer's disease -- In vivo Effect of BRICHOS on Aβ Aggregation and Toxicity
Dimensions
unknown
Extent
XV, 28 p. 13 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319165646
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-16564-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-16564-6
Label
The BRICHOS Domain : Its Proproteins and Functions, by Jenny Presto, Jan Johansson, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction to BRICHOS Superfamily -- BRICHOS in proSP-C -- Proteins with a BRICHOS Domain -- Aβ Amyloid Formation in Alzheimer's disease -- In vivo Effect of BRICHOS on Aβ Aggregation and Toxicity
Dimensions
unknown
Extent
XV, 28 p. 13 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319165646
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-16564-6
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-16564-6

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