The Resource The Hsp60 Chaperonin, by Peter Bross, (electronic resource)

The Hsp60 Chaperonin, by Peter Bross, (electronic resource)

Label
The Hsp60 Chaperonin
Title
The Hsp60 Chaperonin
Statement of responsibility
by Peter Bross
Creator
Contributor
Author
Provider
Subject
Language
eng
Summary
In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular systems and regulatory pathways, especially in connection with neurodegenerative diseases caused by Hsp60 deficiency. Finally, the author highlights controversial observations suggesting additional, non-standard functions of Hsp60 in and outside mitochondria as well as possible gaps in our understanding of the chaperonin. This volume serves as a snapshot suitable for experienced researcher working in fields related to molecular chaperones yet still accessible to researchers entering the field
Member of
http://library.link/vocab/creatorName
Bross, Peter
Image bit depth
0
LC call number
QD431-431.7
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
SpringerLink
Series statement
SpringerBriefs in Molecular Science,
http://library.link/vocab/subjectName
  • Life sciences
  • Molecular biology
  • Bioorganic chemistry
  • Proteins
  • Life Sciences
  • Protein Science
  • Bioorganic Chemistry
  • Molecular Medicine
Label
The Hsp60 Chaperonin, by Peter Bross, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Historical sketch of the discovery and recognition of the function of chaperonins -- Molecular structure of chaperonins -- Folding by enclosure in the chaperonin cavity -- Evolutionary origins and family relations -- Chaperoning mechanisms: folding helpers, folding protectors or misfolding blockers? -- Sequence variations in proteins affecting chaperonin dependence -- Genetic organization of type I chaperonin genes -- Regulation of type I chaperonin gene expression -- Subcellular localization -- Posttranslational modifications -- Variations in Hsp60 and Hsp10 in humans -- Type I chaperonins are essential for cell viability and mutations cause deficiency phenotypes -- Human diseases caused by genetic mutations in the Hsp60/Hsp10 system -- Molecular investigations of disease mechanisms -- Molecular investigations of disease mechanisms -- Outlook
Dimensions
unknown
Edition
1st ed. 2015.
Extent
XI, 85 p. 19 illus., 4 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319260884
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-26088-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-26088-4
Label
The Hsp60 Chaperonin, by Peter Bross, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Historical sketch of the discovery and recognition of the function of chaperonins -- Molecular structure of chaperonins -- Folding by enclosure in the chaperonin cavity -- Evolutionary origins and family relations -- Chaperoning mechanisms: folding helpers, folding protectors or misfolding blockers? -- Sequence variations in proteins affecting chaperonin dependence -- Genetic organization of type I chaperonin genes -- Regulation of type I chaperonin gene expression -- Subcellular localization -- Posttranslational modifications -- Variations in Hsp60 and Hsp10 in humans -- Type I chaperonins are essential for cell viability and mutations cause deficiency phenotypes -- Human diseases caused by genetic mutations in the Hsp60/Hsp10 system -- Molecular investigations of disease mechanisms -- Molecular investigations of disease mechanisms -- Outlook
Dimensions
unknown
Edition
1st ed. 2015.
Extent
XI, 85 p. 19 illus., 4 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319260884
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-26088-4
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-3-319-26088-4

Library Locations

  • African Studies LibraryBorrow it
    771 Commonwealth Avenue, 6th Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Alumni Medical LibraryBorrow it
    72 East Concord Street, Boston, MA, 02118, US
    42.336388 -71.072393
  • Astronomy LibraryBorrow it
    725 Commonwealth Avenue, 6th Floor, Boston, MA, 02445, US
    42.350259 -71.105717
  • Fineman and Pappas Law LibrariesBorrow it
    765 Commonwealth Avenue, Boston, MA, 02215, US
    42.350979 -71.107023
  • Frederick S. Pardee Management LibraryBorrow it
    595 Commonwealth Avenue, Boston, MA, 02215, US
    42.349626 -71.099547
  • Howard Gotlieb Archival Research CenterBorrow it
    771 Commonwealth Avenue, 5th Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Mugar Memorial LibraryBorrow it
    771 Commonwealth Avenue, Boston, MA, 02215, US
    42.350723 -71.108227
  • Music LibraryBorrow it
    771 Commonwealth Avenue, 2nd Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Pikering Educational Resources LibraryBorrow it
    2 Silber Way, Boston, MA, 02215, US
    42.349804 -71.101425
  • School of Theology LibraryBorrow it
    745 Commonwealth Avenue, 2nd Floor, Boston, MA, 02215, US
    42.350494 -71.107235
  • Science & Engineering LibraryBorrow it
    38 Cummington Mall, Boston, MA, 02215, US
    42.348472 -71.102257
  • Stone Science LibraryBorrow it
    675 Commonwealth Avenue, Boston, MA, 02445, US
    42.350103 -71.103784
Processing Feedback ...