The Resource The Role of Microtubules in Cell Biology, Neurobiology, and Oncology, edited by Tito Fojo, (electronic resource)

The Role of Microtubules in Cell Biology, Neurobiology, and Oncology, edited by Tito Fojo, (electronic resource)

Label
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology
Title
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology
Statement of responsibility
edited by Tito Fojo
Creator
Contributor
Editor
Provider
Subject
Language
eng
Summary
The family of proteins called the tubulin and the microtubules they form when they aggregate are extremely important in the cell and, as we are increasingly learning, important in diseases that afflict so many. This field of investigation is a testament to how important both basic and clinical sciences are in understanding disease mechanisms and making inroads into therapies. Microtubule Targets in Cancer Therapy presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available. Among the topics examined in this volume are compounds that interact with tubulin, mechanisms and regulation by microtubule-associated proteins and drugs, MAPs, the tubulin superfamily its isotopes, peptides and depsipeptides, and neurodegenerative diseases. Without the basic scientific knowledge that has been accumulated – to which the contributors of this work have contributed greatly – we would not be in the position we find ourselves as we increasingly understand disease and advancing therapies. Microtubule Targets in Cancer Therapy contributes to this new knowledge, and the text will be an invaluable resource for cancer researchers, oncologists, pharmacologists, and medical chemists
Member of
http://library.link/vocab/creatorName
Fojo, Tito
Image bit depth
0
LC call number
RC261-271
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
SpringerLink
Series statement
Cancer Drug Discovery and Development
http://library.link/vocab/subjectName
  • Medicine
  • Oncology
  • Toxicology
  • Biochemistry
  • Biomedicine
  • Cancer Research
  • Oncology
  • Pharmacology/Toxicology
  • Medicinal Chemistry
Label
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology, edited by Tito Fojo, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
An Overview of Compounds That Interact with Tubulin and Their Effects on Microtubule Assembly -- Molecular Mechanisms of Microtubule Acting Cancer Drugs -- Microtubule Dynamics -- Microtubule-Associated Proteins and Microtubule-Interacting Proteins -- The Post-Translational Modifications of Tubulin -- The Isotypes of Tubulin -- The Tubulin Superfamily -- Tubulin Proteomics in Cancer -- Tubulin and Microtubule Structures -- Destabilizing Agents -- Molecular Features of the Interaction of Colchicine and Related Structures with Tubulin -- Antimicrotubule Agents That Bind Covalently to Tubulin -- Microtubule Stabilizing Agents -- Mechanisms of Resistance to Drugs That Interfere with Microtubule Assembly -- Resistance to Microtubule-Targeting Drugs -- Microtubule Stabilizing Agents in Clinical Oncology -- Investigational Anticancer Agents Targeting the Microtubule -- Microtubule Damaging Agents and Apoptosis -- Microtubule Targeting Agents and the Tumor Vasculature -- Neurodegenerative Diseases -- Structure, Function, and Regulation of the Microtubule Associated Protein Tau
Dimensions
unknown
File format
multiple file formats
Form of item
electronic
Isbn
9781597453363
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-59745-336-3
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-59745-336-3
Label
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology, edited by Tito Fojo, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
An Overview of Compounds That Interact with Tubulin and Their Effects on Microtubule Assembly -- Molecular Mechanisms of Microtubule Acting Cancer Drugs -- Microtubule Dynamics -- Microtubule-Associated Proteins and Microtubule-Interacting Proteins -- The Post-Translational Modifications of Tubulin -- The Isotypes of Tubulin -- The Tubulin Superfamily -- Tubulin Proteomics in Cancer -- Tubulin and Microtubule Structures -- Destabilizing Agents -- Molecular Features of the Interaction of Colchicine and Related Structures with Tubulin -- Antimicrotubule Agents That Bind Covalently to Tubulin -- Microtubule Stabilizing Agents -- Mechanisms of Resistance to Drugs That Interfere with Microtubule Assembly -- Resistance to Microtubule-Targeting Drugs -- Microtubule Stabilizing Agents in Clinical Oncology -- Investigational Anticancer Agents Targeting the Microtubule -- Microtubule Damaging Agents and Apoptosis -- Microtubule Targeting Agents and the Tumor Vasculature -- Neurodegenerative Diseases -- Structure, Function, and Regulation of the Microtubule Associated Protein Tau
Dimensions
unknown
File format
multiple file formats
Form of item
electronic
Isbn
9781597453363
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-59745-336-3
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-59745-336-3

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