The Resource Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure : a systematic review, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Timothy J. Wilt ; investigators, principal investigators, Thomas S. Rector, Brent C. Taylor, research Associates, Nancy Greer, Indulis Rutks, (electronic resource)

Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure : a systematic review, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Timothy J. Wilt ; investigators, principal investigators, Thomas S. Rector, Brent C. Taylor, research Associates, Nancy Greer, Indulis Rutks, (electronic resource)

Label
Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure : a systematic review
Title
Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure
Title remainder
a systematic review
Statement of responsibility
prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Timothy J. Wilt ; investigators, principal investigators, Thomas S. Rector, Brent C. Taylor, research Associates, Nancy Greer, Indulis Rutks
Creator
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
Heart failure is defined as reduced ability of the heart to pump blood and maintain normal bodily function. Heart transplantation is currently the preferred treatment for end-stage heart failure but the supply of donor hearts is insufficient to meet the need and many patients are not eligible for transplantation due to age or comorbid conditions. Implantable mechanical pumps can assist the circulation of blood by the ventricles. Left ventricular assist devices (LVADs) have been approved by the U.S. Food and Drug Administration (FDA) for use in patients awaiting transplant (a bridge to transplant) and as a last resort in patients with refractory heart failure who are not eligible for a heart transplant (destination therapy). In January 2010, the first newer generation, rotary continuous flow ventricular assist device (HeartMate II) was approved by the FDA for destination therapy. Eligibility criteria are essentially the same as those used to select patients for the pivotal clinical trial that included patients with shortness of breath and/or fatigue at rest or during minimal exertion despite treatment with optimal therapy for heart failure associated with a low ejection fraction (< 25%) who were not candidates for heart transplantation due to their age or co-morbid conditions. The purpose of this report is to review the scientific evidence for use of the current generation of left ventricular assist devices as destination therapy
Member of
Cataloging source
DNLM
http://library.link/vocab/creatorName
Rector, Thomas S
Government publication
federal national government publication
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WG 169.5
http://library.link/vocab/relatedWorkOrContributorName
  • Taylor, Brent C
  • Greer, Nancy L
  • Rutks, Indulis
  • Wilt, Timothy J
  • Quality Enhancement Research Initiative (U.S.)
  • United States
  • Veterans Administration Medical Center (Minneapolis, Minn.)
Series statement
Evidence-based synthesis program
http://library.link/vocab/subjectName
  • Heart-Assist Devices
  • Heart Failure
  • Clinical Trials as Topic
  • Models, Theoretical
  • United States
Label
Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure : a systematic review, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Timothy J. Wilt ; investigators, principal investigators, Thomas S. Rector, Brent C. Taylor, research Associates, Nancy Greer, Indulis Rutks, (electronic resource)
Instantiates
Publication
Note
"May 2012."
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource (1 PDF file (iii, 41 p.))
Form of item
online
Other physical details
ill.
Specific material designation
remote
System control number
  • 1592250
  • (DNLM)BKSHLF:NBK99059
Label
Use of left ventricular assist devices as destination therapy in end-stage congestive heart failure : a systematic review, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Timothy J. Wilt ; investigators, principal investigators, Thomas S. Rector, Brent C. Taylor, research Associates, Nancy Greer, Indulis Rutks, (electronic resource)
Publication
Note
"May 2012."
Bibliography note
Includes bibliographical references
Dimensions
unknown
Extent
1 online resource (1 PDF file (iii, 41 p.))
Form of item
online
Other physical details
ill.
Specific material designation
remote
System control number
  • 1592250
  • (DNLM)BKSHLF:NBK99059

Library Locations

  • African Studies LibraryBorrow it
    771 Commonwealth Avenue, 6th Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Alumni Medical LibraryBorrow it
    72 East Concord Street, Boston, MA, 02118, US
    42.336388 -71.072393
  • Astronomy LibraryBorrow it
    725 Commonwealth Avenue, 6th Floor, Boston, MA, 02445, US
    42.350259 -71.105717
  • Fineman and Pappas Law LibrariesBorrow it
    765 Commonwealth Avenue, Boston, MA, 02215, US
    42.350979 -71.107023
  • Frederick S. Pardee Management LibraryBorrow it
    595 Commonwealth Avenue, Boston, MA, 02215, US
    42.349626 -71.099547
  • Howard Gotlieb Archival Research CenterBorrow it
    771 Commonwealth Avenue, 5th Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Mugar Memorial LibraryBorrow it
    771 Commonwealth Avenue, Boston, MA, 02215, US
    42.350723 -71.108227
  • Music LibraryBorrow it
    771 Commonwealth Avenue, 2nd Floor, Boston, MA, 02215, US
    42.350723 -71.108227
  • Pikering Educational Resources LibraryBorrow it
    2 Silber Way, Boston, MA, 02215, US
    42.349804 -71.101425
  • School of Theology LibraryBorrow it
    745 Commonwealth Avenue, 2nd Floor, Boston, MA, 02215, US
    42.350494 -71.107235
  • Science & Engineering LibraryBorrow it
    38 Cummington Mall, Boston, MA, 02215, US
    42.348472 -71.102257
  • Stone Science LibraryBorrow it
    675 Commonwealth Avenue, Boston, MA, 02445, US
    42.350103 -71.103784
Processing Feedback ...