The Resource mTOR Pathway and mTOR Inhibitors in Cancer Therapy, edited by Vitaly A. Polunovsky, Peter J. Houghton, (electronic resource)

mTOR Pathway and mTOR Inhibitors in Cancer Therapy, edited by Vitaly A. Polunovsky, Peter J. Houghton, (electronic resource)

Label
mTOR Pathway and mTOR Inhibitors in Cancer Therapy
Title
mTOR Pathway and mTOR Inhibitors in Cancer Therapy
Statement of responsibility
edited by Vitaly A. Polunovsky, Peter J. Houghton
Creator
Contributor
Editor
Provider
Subject
Language
eng
Summary
mTOR Pathway and mTOR Inhibitors in Cancer Therapy provides an up-to-date survey of the rapidly advancing field of cancer therapy. Our understanding of the mechanisms involved in cancer genesis and progression underwent unprecedented expansion during the last decade, opening a new era of cancer treatment – targeted therapy. The surge in this area results in no small part from studies conducted jointly by basic health scientists and clinical investigators. It is our hope that this book will help foster even further collaboration between investigators in these two disciplines. In this work, experts in TOR signaling have contributed in two thematic areas: mTOR Signaling and Cancer Therapy (chapters 1 - 8) and Therapeutic Targeting Downstream of mTOR (chapter 9 – 13). All chapters of mTOR Pathway and mTOR Inhibitors in Cancer Therapy are completely new or have been extensively updated by their authors; and we are indebted to all authors who have exemplified the links between these 2 thematic areas
Member of
http://library.link/vocab/creatorName
Polunovskiĭ, V. A.
Image bit depth
0
LC call number
RC261-271
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Houghton, Peter J.
  • SpringerLink
Series statement
Cancer Drug Discovery and Development
http://library.link/vocab/subjectName
  • Medicine
  • Oncology
  • Toxicology
  • Cytology
  • Biomedicine
  • Cancer Research
  • Cell Biology
  • Pharmacology/Toxicology
Label
mTOR Pathway and mTOR Inhibitors in Cancer Therapy, edited by Vitaly A. Polunovsky, Peter J. Houghton, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
mTORC1: A Signaling Integration Node Involved in Cell Growth -- The Regulation of the IGF-1/mTOR Pathway by the p53 Tumor Suppressor Gene Functions -- mTOR Signaling in Angiogenesis -- mTORC1 Signaling and Hypoxia -- mTOR Signaling in Glioblastoma: Lessons Learned from Bench to Bedside -- mTOR and Cancer Therapy: General Principles -- mTOR and Cancer Therapy: Clinical Development and Novel Prospects -- Drug Combinations as a Therapeutic Approach for mTORC1 Inhibitors in Human Cancer -- Downstream Targets of mTORC1 -- Downstream of mTOR: Translational Control of Cancer -- Genome-Wide Analysis of Translational Control -- Translational Control of Cancer: Implications for Targeted Therapy -- Downstream from mTOR: Therapeutic Approaches to Targeting the eIF4F Translation Initiation Complex
Dimensions
unknown
Extent
XII, 304 p.
File format
multiple file formats
Form of item
electronic
Isbn
9781603272711
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-60327-271-1
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-60327-271-1
Label
mTOR Pathway and mTOR Inhibitors in Cancer Therapy, edited by Vitaly A. Polunovsky, Peter J. Houghton, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
mTORC1: A Signaling Integration Node Involved in Cell Growth -- The Regulation of the IGF-1/mTOR Pathway by the p53 Tumor Suppressor Gene Functions -- mTOR Signaling in Angiogenesis -- mTORC1 Signaling and Hypoxia -- mTOR Signaling in Glioblastoma: Lessons Learned from Bench to Bedside -- mTOR and Cancer Therapy: General Principles -- mTOR and Cancer Therapy: Clinical Development and Novel Prospects -- Drug Combinations as a Therapeutic Approach for mTORC1 Inhibitors in Human Cancer -- Downstream Targets of mTORC1 -- Downstream of mTOR: Translational Control of Cancer -- Genome-Wide Analysis of Translational Control -- Translational Control of Cancer: Implications for Targeted Therapy -- Downstream from mTOR: Therapeutic Approaches to Targeting the eIF4F Translation Initiation Complex
Dimensions
unknown
Extent
XII, 304 p.
File format
multiple file formats
Form of item
electronic
Isbn
9781603272711
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-60327-271-1
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(DE-He213)978-1-60327-271-1

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